Entity Details

Primary name SLIT1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO75093
EntryNameSLIT1_HUMAN
FullNameSlit homolog 1 protein
TaxID9606
Evidenceevidence at protein level
Length1534
SequenceStatuscomplete
DateCreated2004-03-15
DateModified2021-06-02

Ontological Relatives

GenesSLIT1

GO terms

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GOName
GO:0005509 calcium ion binding
GO:0005615 extracellular space
GO:0007097 nuclear migration
GO:0007411 axon guidance
GO:0008045 motor neuron axon guidance
GO:0008201 heparin binding
GO:0022028 tangential migration from the subventricular zone to the olfactory bulb
GO:0031290 retinal ganglion cell axon guidance
GO:0033563 dorsal/ventral axon guidance
GO:0048495 Roundabout binding
GO:0048846 axon extension involved in axon guidance
GO:0048853 forebrain morphogenesis
GO:0050919 negative chemotaxis
GO:0051964 negative regulation of synapse assembly

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR000152 EGF-type aspartate/asparagine hydroxylation sitePTMPTM
IPR000372 Leucine-rich repeat N-terminal domainDomainDomain
IPR000483 Cysteine-rich flanking region, C-terminalDomainDomain
IPR000742 EGF-like domainDomainDomain
IPR001611 Leucine-rich repeatRepeatRepeat
IPR001791 Laminin G domainDomainDomain
IPR001881 EGF-like calcium-binding domainDomainDomain
IPR003591 Leucine-rich repeat, typical subtypeRepeatRepeat
IPR003645 Follistatin-like, N-terminalDomainDomain
IPR006207 Cystine knot, C-terminalDomainDomain
IPR009030 Growth factor receptor cysteine-rich domain superfamilyFamilyHomologous superfamily
IPR013032 EGF-like, conserved siteSiteConserved site
IPR013320 Concanavalin A-like lectin/glucanase domain superfamilyFamilyHomologous superfamily
IPR018097 EGF-like calcium-binding, conserved siteSiteConserved site
IPR032675 Leucine-rich repeat domain superfamilyFamilyHomologous superfamily

Diseases

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