Entity Details

Primary name ERLN1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO75477
EntryNameERLN1_HUMAN
FullNameErlin-1
TaxID9606
Evidenceevidence at protein level
Length348
SequenceStatuscomplete
DateCreated2005-06-07
DateModified2021-06-02

Ontological Relatives

GenesERLIN1

GO terms

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GOName
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0008203 cholesterol metabolic process
GO:0015485 cholesterol binding
GO:0016021 integral component of membrane
GO:0030433 ubiquitin-dependent ERAD pathway
GO:0031625 ubiquitin protein ligase binding
GO:0032933 SREBP signaling pathway
GO:0032991 protein-containing complex
GO:0045541 negative regulation of cholesterol biosynthetic process
GO:0045717 negative regulation of fatty acid biosynthetic process
GO:0055085 transmembrane transport

Subcellular Location

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Subcellular Location
Endoplasmic reticulum membrane

Domains

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DomainNameCategoryType
IPR001107 Band 7 domainDomainDomain
IPR033294 Erlin1/2FamilyFamily
IPR036013 Band 7/SPFH domain superfamilyFamilyHomologous superfamily

Diseases

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