Entity Details

Primary name FACE1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO75844
EntryNameFACE1_HUMAN
FullNameCAAX prenyl protease 1 homolog
TaxID9606
Evidenceevidence at protein level
Length475
SequenceStatuscomplete
DateCreated1999-07-15
DateModified2021-06-02

Ontological Relatives

GenesZMPSTE24

GO terms

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GOName
GO:0001889 liver development
GO:0001942 hair follicle development
GO:0003007 heart morphogenesis
GO:0003229 ventricular cardiac muscle tissue development
GO:0003231 cardiac ventricle development
GO:0003417 growth plate cartilage development
GO:0003690 double-stranded DNA binding
GO:0004222 metalloendopeptidase activity
GO:0005637 nuclear inner membrane
GO:0006281 DNA repair
GO:0006508 proteolysis
GO:0006925 inflammatory cell apoptotic process
GO:0006998 nuclear envelope organization
GO:0007628 adult walking behavior
GO:0008235 metalloexopeptidase activity
GO:0008340 determination of adult lifespan
GO:0008360 regulation of cell shape
GO:0010506 regulation of autophagy
GO:0010906 regulation of glucose metabolic process
GO:0016020 membrane
GO:0019216 regulation of lipid metabolic process
GO:0030176 integral component of endoplasmic reticulum membrane
GO:0030282 bone mineralization
GO:0030327 prenylated protein catabolic process
GO:0030500 regulation of bone mineralization
GO:0032006 regulation of TOR signaling
GO:0032350 regulation of hormone metabolic process
GO:0032991 protein-containing complex
GO:0035264 multicellular organism growth
GO:0040014 regulation of multicellular organism growth
GO:0043007 maintenance of rDNA
GO:0043516 regulation of DNA damage response, signal transduction by p53 class mediator
GO:0043979 histone H2B-K5 acetylation
GO:0044029 hypomethylation of CpG island
GO:0044255 cellular lipid metabolic process
GO:0046872 metal ion binding
GO:0048145 regulation of fibroblast proliferation
GO:0048538 thymus development
GO:0050688 regulation of defense response to virus
GO:0050905 neuromuscular process
GO:0060307 regulation of ventricular cardiac muscle cell membrane repolarization
GO:0060993 kidney morphogenesis
GO:0061337 cardiac conduction
GO:0061762 CAMKK-AMPK signaling cascade
GO:0070062 extracellular exosome
GO:0070302 regulation of stress-activated protein kinase signaling cascade
GO:0071480 cellular response to gamma radiation
GO:0071586 CAAX-box protein processing
GO:0072423 response to DNA damage checkpoint signaling
GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding
GO:1903463 regulation of mitotic cell cycle DNA replication
GO:1903799 negative regulation of production of miRNAs involved in gene silencing by miRNA
GO:1990036 calcium ion import into sarcoplasmic reticulum
GO:1990164 histone H2A phosphorylation
GO:2000618 regulation of histone H4-K16 acetylation
GO:2000730 regulation of termination of RNA polymerase I transcription
GO:2000772 regulation of cellular senescence

Subcellular Location

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Subcellular Location
Endoplasmic reticulum membrane
Nucleus inner membrane

Domains

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DomainNameCategoryType
IPR001915 Peptidase M48DomainDomain
IPR027057 CAAX prenyl protease 1FamilyFamily
IPR032456 CAAX prenyl protease 1, N-terminalDomainDomain

Diseases

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