Entity Details

Primary name RECQ5_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO94762
EntryNameRECQ5_HUMAN
FullNameATP-dependent DNA helicase Q5
TaxID9606
Evidenceevidence at protein level
Length991
SequenceStatuscomplete
DateCreated2000-05-30
DateModified2021-06-02

Ontological Relatives

GenesRECQL5

GO terms

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GOName
GO:0000278 mitotic cell cycle
GO:0000724 double-strand break repair via homologous recombination
GO:0000993 RNA polymerase II complex binding
GO:0003676 nucleic acid binding
GO:0003678 DNA helicase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006259 DNA metabolic process
GO:0006260 DNA replication
GO:0006268 DNA unwinding involved in DNA replication
GO:0006281 DNA repair
GO:0006310 DNA recombination
GO:0009378 four-way junction helicase activity
GO:0016591 RNA polymerase II, holoenzyme
GO:0032508 DNA duplex unwinding
GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter
GO:0035690 cellular response to drug
GO:0042802 identical protein binding
GO:0043138 3'-5' DNA helicase activity
GO:0051301 cell division
GO:0051304 chromosome separation
GO:0072757 cellular response to camptothecin
GO:1990414 replication-born double-strand break repair via sister chromatid exchange
GO:2000042 negative regulation of double-strand break repair via homologous recombination

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR001650 Helicase, C-terminalDomainDomain
IPR002464 DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved siteSiteConserved site
IPR004589 DNA helicase, ATP-dependent, RecQ typeFamilyFamily
IPR010716 RecQ helicase-like 5DomainDomain
IPR011545 DEAD/DEAH box helicase domainDomainDomain
IPR014001 Helicase superfamily 1/2, ATP-binding domainDomainDomain
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domainDomainDomain

Diseases

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Interactions

33 interactions

InteractorPartnerSourcesPublicationsLink
RECQ5_HUMANEF1G_HUMANBioGRID, HPRD, IntAct16169070 details
RECQ5_HUMANTIMP1_HUMANBioGRID, HPRD, IntAct16169070 details
RECQ5_HUMANCREB1_HUMANBioGRID, HPRD, IntAct16169070 details
RECQ5_HUMANPLK1_HUMANBioGRID, HPRD, IntAct16169070 details
RECQ5_HUMANCUX1_HUMANBioGRID, HPRD, IntAct16169070 details
RECQ5_HUMANDDX42_HUMANBioGRID, HPRD, IntAct16169070 details
RECQ5_HUMANCENPR_HUMANBioGRID, HPRD, IntAct16169070 details
RECQ5_HUMANJIP1_HUMANBioGRID, HPRD, IntAct16169070 details
RECQ5_HUMANMTSS1_HUMANBioGRID, HPRD, IntAct16169070 details
RECQ5_HUMANAL7A1_HUMANHPRD, IntAct16169070 details
RECQ5_HUMANSTABP_HUMANHPRD, IntAct16169070 details
RECQ5_HUMANBNIPL_HUMANBioGRID, IntAct21988832 details
RECQ5_HUMANRPB1_HUMANBioGRID, DIP18562274 19270065 20705653 21402780 23748380 24981860 27502483 32900933 details
RECQ5_HUMANRAD51_HUMANBioGRID, DIP18562274 20348101 22645136 details
RECQ5_HUMANPCNA_HUMANBioGRID, DIP18562274 32900933 details
RECQ5_HUMANRECQ5_HUMANDIP23748380 details
RECQ5_HUMANCASP_HUMANBioGRID16169070 details
RECQ5_HUMANMRE11_HUMANBioGRID19270065 details
RECQ5_HUMANRAD50_HUMANBioGRID19270065 details
RECQ5_HUMANNBN_HUMANBioGRID19270065 details
RECQ5_HUMANMUS81_HUMANBioGRID28575661 details
RECQ5_HUMANRPB2_HUMANBioGRID, DIP18562274 19270065 24981860 32900933 details
RECQ5_HUMANTOP3A_HUMANBioGRID, HPRD10710432 details
RECQ5_HUMANTOP3B_HUMANBioGRID, HPRD10710432 details
RECQ5_HUMANPRKDC_HUMANBioGRID19270065 details
RECQ5_HUMANRECQ4_HUMANBioGRID19270065 details
RECQ5_HUMANMCM7_HUMANBioGRID19270065 details
RECQ5_HUMANNUCL_HUMANBioGRID19270065 details
RECQ5_HUMANUBR5_HUMANBioGRID19270065 details
RECQ5_HUMANRPA1_HUMANBioGRID27502483 details
RECQ5_HUMANMCE1_HUMANBioGRID24981860 29395067 details
RECQ5_HUMANSPT5H_HUMANBioGRID29395067 details
RECQ5_HUMANTIF1B_HUMANBioGRID32900933 details