Entity Details

Primary name GLSK_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO94925
EntryNameGLSK_HUMAN
FullNameGlutaminase kidney isoform, mitochondrial
TaxID9606
Evidenceevidence at protein level
Length669
SequenceStatuscomplete
DateCreated2001-01-24
DateModified2021-06-02

Ontological Relatives

GenesGLS

GO terms

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GOName
GO:0001967 suckling behavior
GO:0002087 regulation of respiratory gaseous exchange by nervous system process
GO:0004359 glutaminase activity
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0005829 cytosol
GO:0006537 glutamate biosynthetic process
GO:0006543 glutamine catabolic process
GO:0006836 neurotransmitter transport
GO:0007268 chemical synaptic transmission
GO:0009064 glutamine family amino acid metabolic process
GO:0045202 synapse
GO:0051289 protein homotetramerization
GO:0090461 glutamate homeostasis

Subcellular Location

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Subcellular Location
Cytoplasm
Mitochondrion
Mitochondrion matrix

Domains

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DomainNameCategoryType
IPR002110 Ankyrin repeatRepeatRepeat
IPR012338 Beta-lactamase/transpeptidase-likeFamilyHomologous superfamily
IPR015868 GlutaminaseFamilyFamily
IPR020683 Ankyrin repeat-containing domainDomainDomain
IPR036770 Ankyrin repeat-containing domain superfamilyFamilyHomologous superfamily
IPR041541 Glutaminase, EF-hand domainDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB00130 L-GlutamineDrugbanksmall molecule
DB00142 Glutamic acidDrugbanksmall molecule
DB09374 Indocyanine green acid formSwissprotsmall molecule
DB13155 EsculinDrugbanksmall molecule