Entity Details

Primary name ZBT7A_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO95365
EntryNameZBT7A_HUMAN
FullNameZinc finger and BTB domain-containing protein 7A
TaxID9606
Evidenceevidence at protein level
Length584
SequenceStatuscomplete
DateCreated2004-04-13
DateModified2021-06-02

Ontological Relatives

GenesZBTB7A

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000381 regulation of alternative mRNA splicing, via spliceosome
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001222 transcription corepressor binding
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0006110 regulation of glycolytic process
GO:0006325 chromatin organization
GO:0006338 chromatin remodeling
GO:0006351 transcription, DNA-templated
GO:0006357 regulation of transcription by RNA polymerase II
GO:0030183 B cell differentiation
GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway
GO:0034504 protein localization to nucleus
GO:0035035 histone acetyltransferase binding
GO:0035861 site of double-strand break
GO:0042981 regulation of apoptotic process
GO:0043249 erythrocyte maturation
GO:0045444 fat cell differentiation
GO:0045746 negative regulation of Notch signaling pathway
GO:0045892 negative regulation of transcription, DNA-templated
GO:0046332 SMAD binding
GO:0046872 metal ion binding
GO:0050681 androgen receptor binding
GO:0051090 regulation of DNA-binding transcription factor activity
GO:0051092 positive regulation of NF-kappaB transcription factor activity
GO:0060766 negative regulation of androgen receptor signaling pathway
GO:0070418 DNA-dependent protein kinase complex
GO:0097680 double-strand break repair via classical nonhomologous end joining
GO:1990837 sequence-specific double-stranded DNA binding
GO:2000677 regulation of transcription regulatory region DNA binding

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR000210 BTB/POZ domainDomainDomain
IPR011333 SKP1/BTB/POZ domain superfamilyFamilyHomologous superfamily
IPR013087 Zinc finger C2H2-typeDomainDomain
IPR036236 Zinc finger C2H2 superfamilyFamilyHomologous superfamily

Diseases

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Interactions

48 interactions

InteractorPartnerSourcesPublicationsLink
ZBT7A_HUMANPKCB1_HUMANBioGRID, IntAct21988832 details
ZBT7A_HUMANKHDR1_HUMANBioGRID, MINT24514149 details
ZBT7A_HUMANHOMEZ_HUMANBioGRID, IntAct25416956 details
ZBT7A_HUMANCHD3_HUMANBioGRID, DIP23658227 26816381 details
ZBT7A_HUMANP66B_HUMANDIP26816381 details
ZBT7A_HUMANCHD8_HUMANBioGRID, DIP26446488 26816381 details
ZBT7A_HUMANZBTB5_HUMANDIP26816381 details
ZBT7A_HUMANZBT22_HUMANDIP26816381 details
ZBT7A_HUMANZBT45_HUMANDIP26816381 details
ZBT7A_HUMANBAZ1A_HUMANDIP26816381 details
ZBT7A_HUMANSRCAP_HUMANDIP26816381 details
ZBT7A_HUMANZBT7A_HUMANBioGRID, HPRD17189472 21804610 9973611 details
ZBT7A_HUMANBCL6_HUMANBioGRID9927193 details
ZBT7A_HUMANP53_HUMANBioGRID19244234 24857950 details
ZBT7A_HUMANNCOR1_HUMANBioGRID19244234 20812024 23658227 details
ZBT7A_HUMANNCOR2_HUMANBioGRID19244234 20812024 23658227 details
ZBT7A_HUMANBCOR_HUMANBioGRID18801742 23658227 details
ZBT7A_HUMANANDR_HUMANBioGRID20812024 31444154 details
ZBT7A_HUMANTF65_HUMANBioGRID15917220 29813070 details
ZBT7A_HUMANIKBB_HUMANBioGRID15917220 details
ZBT7A_HUMANTZAP_HUMANBioGRID24382891 details
ZBT7A_HUMANUBC9_HUMANBioGRID17595526 details
ZBT7A_HUMANSMAD4_HUMANBioGRID25514493 details
ZBT7A_HUMANCRBN_HUMANBioGRID30385546 details
ZBT7A_HUMANMBD3_HUMANBioGRID23658227 details
ZBT7A_HUMANXRCC5_HUMANBioGRID26446488 details
ZBT7A_HUMANXRCC6_HUMANBioGRID26446488 details
ZBT7A_HUMANPRKDC_HUMANBioGRID26446488 details
ZBT7A_HUMANHDAC1_HUMANBioGRID, DIP, MINT19244234 23658227 24514149 25514493 26816381 31444154 details
ZBT7A_HUMANHDAC2_HUMANBioGRID, DIP19244234 26816381 details
ZBT7A_HUMANMTA2_HUMANBioGRID, DIP23658227 26446488 26816381 details
ZBT7A_HUMANHDAC3_HUMANBioGRID19244234 details
ZBT7A_HUMANSIR1_HUMANBioGRID19244234 details
ZBT7A_HUMANSIN3A_HUMANBioGRID19244234 details
ZBT7A_HUMANRB_HUMANBioGRID18801742 31444154 details
ZBT7A_HUMANSP1_HUMANBioGRID, HPRD12004059 18368381 details
ZBT7A_HUMANEF1A1_HUMANBioGRID19471103 details
ZBT7A_HUMANSRBP1_HUMANBioGRID18682402 details
ZBT7A_HUMANIKBA_HUMANBioGRID15917220 details
ZBT7A_HUMANSOX9_HUMANBioGRID23727861 details
ZBT7A_HUMANETS1_HUMANBioGRID24857950 details
ZBT7A_HUMANIF4G2_HUMANBioGRID28849590 details
ZBT7A_HUMANDNMT1_HUMANBioGRID23658227 details
ZBT7A_HUMANDNM3B_HUMANBioGRID23658227 details
ZBT7A_HUMANCBX5_HUMANBioGRID23658227 details
ZBT7A_HUMANE2F1_HUMANBioGRID31444154 details
ZBT7A_HUMANSP4_HUMANHPRD12004059 details
ZBT7A_HUMANSP3_HUMANHPRD12004059 details