Entity Details

Primary name KAD1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP00568
EntryNameKAD1_HUMAN
FullNameAdenylate kinase isoenzyme 1
TaxID9606
Evidenceevidence at protein level
Length194
SequenceStatuscomplete
DateCreated1986-07-21
DateModified2021-06-02

Ontological Relatives

GenesAK1

GO terms

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GOName
GO:0004017 adenylate kinase activity
GO:0004550 nucleoside diphosphate kinase activity
GO:0005524 ATP binding
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006165 nucleoside diphosphate phosphorylation
GO:0006172 ADP biosynthetic process
GO:0009142 nucleoside triphosphate biosynthetic process
GO:0015949 nucleobase-containing small molecule interconversion
GO:0046033 AMP metabolic process
GO:0046034 ATP metabolic process
GO:0070062 extracellular exosome

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR000850 Adenylate kinase/UMP-CMP kinaseFamilyFamily
IPR006267 Adenylate kinase, isozyme 1/5FamilyFamily
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR028582 Adenylate kinase isoenzyme 1FamilyFamily
IPR033690 Adenylate kinase, conserved siteSiteConserved site

Diseases

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Drugs

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DrugNameSourceType
DB01717 Bis(Adenosine)-5'-PentaphosphateDrugbanksmall molecule
DB09299 Tenofovir alafenamideDrugbanksmall molecule
DB14126 TenofovirDrugbanksmall molecule

Interactions

7 interactions