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Entity Details
Primary name
H10_HUMAN
Entity type
UniProt
Source
Source Link
Details
Accession
P07305
EntryName
H10_HUMAN
FullName
Histone H1.0
TaxID
9606
Evidence
evidence at protein level
Length
194
SequenceStatus
complete
DateCreated
1988-04-01
DateModified
2021-06-02
Ontological Relatives
Genes
H1-0
GO terms
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GO
Name
GO:0000122
negative regulation of transcription by RNA polymerase II
GO:0000785
chromatin
GO:0000786
nucleosome
GO:0000791
euchromatin
GO:0003680
minor groove of adenine-thymine-rich DNA binding
GO:0003690
double-stranded DNA binding
GO:0003723
RNA binding
GO:0005634
nucleus
GO:0005654
nucleoplasm
GO:0005794
Golgi apparatus
GO:0006309
apoptotic DNA fragmentation
GO:0006334
nucleosome assembly
GO:0006342
chromatin silencing
GO:0015629
actin cytoskeleton
GO:0016584
nucleosome positioning
GO:0016604
nuclear body
GO:0017053
transcription repressor complex
GO:0030261
chromosome condensation
GO:0031490
chromatin DNA binding
GO:0031492
nucleosomal DNA binding
GO:0031936
negative regulation of chromatin silencing
GO:0045910
negative regulation of DNA recombination
GO:2000679
positive regulation of transcription regulatory region DNA binding
Subcellular Location
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Subcellular Location
Chromosome
Nucleus
Domains
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Domain
Name
Category
Type
IPR005818
Linker histone H1/H5, domain H15
Domain
Domain
IPR005819
Linker histone H1/H5
Family
Family
IPR036388
Winged helix-like DNA-binding domain superfamily
Family
Homologous superfamily
IPR036390
Winged helix DNA-binding domain superfamily
Family
Homologous superfamily
Diseases
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Drugs
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Interactions
29 interactions
Interactor
Partner
Sources
Publications
Link
H10_HUMAN
RA51B_HUMAN
HPRD, MINT
14595808
4595808
details
H10_HUMAN
NOA1_HUMAN
HPRD, IntAct
16169070
details
H10_HUMAN
GRB2_HUMAN
BioGRID, IntAct
18624398
details
H10_HUMAN
NEMO_HUMAN
BioGRID, IntAct
20098747
details
H10_HUMAN
CDK2_HUMAN
BioGRID, DIP
12383116
12800980
12949733
12970441
15147269
16365885
16985050
17224799
17361108
18719096
19829063
details
H10_HUMAN
RN168_HUMAN
DIP
26503038
details
H10_HUMAN
XBP1_HUMAN
BioGRID, IntAct
20211142
details
H10_HUMAN
NED4L_HUMAN
BioGRID
19953087
details
H10_HUMAN
CCNE1_HUMAN
BioGRID
17361108
details
H10_HUMAN
CDK5_HUMAN
BioGRID
12970441
details
H10_HUMAN
CDK4_HUMAN
BioGRID
12383116
details
H10_HUMAN
CDK1_HUMAN
BioGRID
12190313
15147269
8034666
details
H10_HUMAN
A4_HUMAN
BioGRID
21832049
details
H10_HUMAN
KPCB_HUMAN
BioGRID
8034666
details
H10_HUMAN
PARP1_HUMAN
BioGRID
28190768
details
H10_HUMAN
PARP2_HUMAN
BioGRID
28190768
details
H10_HUMAN
HPF1_HUMAN
BioGRID
28190768
details
H10_HUMAN
FBX7_HUMAN
BioGRID
27503909
details
H10_HUMAN
HSP77_HUMAN
IntAct
30021884
details
H10_HUMAN
LORF2_HUMAN
IntAct
30021884
details
H10_HUMAN
FMR1_HUMAN
IntAct
31413325
details
H10_HUMAN
1433T_HUMAN
BioGRID
20618440
details
H10_HUMAN
ERCC8_HUMAN
BioGRID
22902626
details
H10_HUMAN
UB2E1_HUMAN
BioGRID
28073915
details
H10_HUMAN
GRSF1_HUMAN
BioGRID
29395067
details
H10_HUMAN
IMA1_HUMAN
HPRD
10228156
details
H10_HUMAN
IPO5_HUMAN
HPRD
10228156
details
H10_HUMAN
IMB1_HUMAN
HPRD
10228156
details
H10_HUMAN
IPO7_HUMAN
HPRD
10228156
details
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