Entity Details

Primary name CO8G_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP07360
EntryNameCO8G_HUMAN
FullNameComplement component C8 gamma chain
TaxID9606
Evidenceevidence at protein level
Length202
SequenceStatuscomplete
DateCreated1988-04-01
DateModified2021-06-02

Ontological Relatives

GenesC8G

GO terms

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GOName
GO:0001848 complement binding
GO:0005576 extracellular region
GO:0005579 membrane attack complex
GO:0006956 complement activation
GO:0006957 complement activation, alternative pathway
GO:0006958 complement activation, classical pathway
GO:0019835 cytolysis
GO:0019841 retinol binding
GO:0030449 regulation of complement activation
GO:0044877 protein-containing complex binding
GO:0070062 extracellular exosome
GO:0072562 blood microparticle

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR000566 Lipocalin/cytosolic fatty-acid binding domainDomainDomain
IPR002968 Alpha-1-microglobulinFamilyFamily
IPR012674 CalycinFamilyHomologous superfamily
IPR022272 Lipocalin family conserved siteSiteConserved site
IPR043245 Complement component C8 gamma chainFamilyFamily

Diseases

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Drugs

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DrugNameSourceType
DB01593 ZincDrugbanksmall molecule
DB03017 Lauric acidDrugbanksmall molecule
DB04272 Citric acidDrugbanksmall molecule
DB14487 Zinc acetateDrugbanksmall molecule

Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
CO8G_HUMANUBQL2_HUMANBioGRID, IntAct32296183 details
CO8G_HUMANCO8A_HUMANBioGRID, HPRD11041874 details