Entity Details

Primary name HEM3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP08397
EntryNameHEM3_HUMAN
FullNamePorphobilinogen deaminase
TaxID9606
Evidenceevidence at protein level
Length361
SequenceStatuscomplete
DateCreated1988-08-01
DateModified2021-06-02

Ontological Relatives

GenesHMBS

GO terms

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GOName
GO:0004418 hydroxymethylbilane synthase activity
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006782 protoporphyrinogen IX biosynthetic process
GO:0006783 heme biosynthetic process
GO:0018160 peptidyl-pyrromethane cofactor linkage

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR000860 Porphobilinogen deaminaseFamilyFamily
IPR022417 Porphobilinogen deaminase, N-terminalDomainDomain
IPR022418 Porphobilinogen deaminase, C-terminalDomainDomain
IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding siteSiteBinding site
IPR036803 Porphobilinogen deaminase, C-terminal domain superfamilyFamilyHomologous superfamily

Diseases

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