Entity Details

Primary name CD14_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP08571
EntryNameCD14_HUMAN
FullNameMonocyte differentiation antigen CD14
TaxID9606
Evidenceevidence at protein level
Length375
SequenceStatuscomplete
DateCreated1988-08-01
DateModified2021-06-02

Ontological Relatives

GenesCD14

GO terms

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GOName
GO:0001530 lipopolysaccharide binding
GO:0001847 opsonin receptor activity
GO:0002224 toll-like receptor signaling pathway
GO:0002755 MyD88-dependent toll-like receptor signaling pathway
GO:0002756 MyD88-independent toll-like receptor signaling pathway
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0006898 receptor-mediated endocytosis
GO:0006909 phagocytosis
GO:0006915 apoptotic process
GO:0006954 inflammatory response
GO:0007166 cell surface receptor signaling pathway
GO:0007249 I-kappaB kinase/NF-kappaB signaling
GO:0009408 response to heat
GO:0009897 external side of plasma membrane
GO:0010008 endosome membrane
GO:0016019 peptidoglycan immune receptor activity
GO:0030667 secretory granule membrane
GO:0031362 anchored component of external side of plasma membrane
GO:0031663 lipopolysaccharide-mediated signaling pathway
GO:0032026 response to magnesium ion
GO:0032481 positive regulation of type I interferon production
GO:0032729 positive regulation of interferon-gamma production
GO:0032757 positive regulation of interleukin-8 production
GO:0032760 positive regulation of tumor necrosis factor production
GO:0034128 negative regulation of MyD88-independent toll-like receptor signaling pathway
GO:0034142 toll-like receptor 4 signaling pathway
GO:0034612 response to tumor necrosis factor
GO:0035666 TRIF-dependent toll-like receptor signaling pathway
GO:0038123 toll-like receptor TLR1:TLR2 signaling pathway
GO:0038124 toll-like receptor TLR6:TLR2 signaling pathway
GO:0043312 neutrophil degranulation
GO:0045087 innate immune response
GO:0045121 membrane raft
GO:0045471 response to ethanol
GO:0045807 positive regulation of endocytosis
GO:0046696 lipopolysaccharide receptor complex
GO:0051602 response to electrical stimulus
GO:0070062 extracellular exosome
GO:0070266 necroptotic process
GO:0070891 lipoteichoic acid binding
GO:0071219 cellular response to molecule of bacterial origin
GO:0071222 cellular response to lipopolysaccharide
GO:0071223 cellular response to lipoteichoic acid
GO:0071723 lipopeptide binding
GO:0071726 cellular response to diacyl bacterial lipopeptide
GO:0071727 cellular response to triacyl bacterial lipopeptide
GO:0097190 apoptotic signaling pathway
GO:1901224 positive regulation of NIK/NF-kappaB signaling

Subcellular Location

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Subcellular Location
Cell membrane
Golgi apparatus
Membrane raft
Secreted

Domains

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DomainNameCategoryType
IPR001611 Leucine-rich repeatRepeatRepeat
IPR016337 Monocyte differentiation antigen CD14FamilyFamily
IPR032675 Leucine-rich repeat domain superfamilyFamilyHomologous superfamily

Diseases

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