Entity Details

Primary name LEG1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP09382
EntryNameLEG1_HUMAN
FullNameGalectin-1
TaxID9606
Evidenceevidence at protein level
Length135
SequenceStatuscomplete
DateCreated1989-07-01
DateModified2021-06-02

Ontological Relatives

GenesLGALS1

GO terms

Show/Hide Table
GOName
GO:0002317 plasma cell differentiation
GO:0003723 RNA binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005788 endoplasmic reticulum lumen
GO:0005829 cytosol
GO:0006915 apoptotic process
GO:0009986 cell surface
GO:0010812 negative regulation of cell-substrate adhesion
GO:0010977 negative regulation of neuron projection development
GO:0030246 carbohydrate binding
GO:0030395 lactose binding
GO:0031295 T cell costimulation
GO:0034120 positive regulation of erythrocyte aggregation
GO:0035900 response to isolation stress
GO:0042493 response to drug
GO:0042802 identical protein binding
GO:0042981 regulation of apoptotic process
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043236 laminin binding
GO:0043687 post-translational protein modification
GO:0044267 cellular protein metabolic process
GO:0045445 myoblast differentiation
GO:0046598 positive regulation of viral entry into host cell
GO:0048678 response to axon injury
GO:0062023 collagen-containing extracellular matrix
GO:0070062 extracellular exosome
GO:0071333 cellular response to glucose stimulus
GO:0071407 cellular response to organic cyclic compound

Subcellular Location

Show/Hide Table
Subcellular Location
Cytoplasm
Secreted

Domains

Show/Hide Table
DomainNameCategoryType
IPR001079 Galectin, carbohydrate recognition domainDomainDomain
IPR013320 Concanavalin A-like lectin/glucanase domain superfamilyFamilyHomologous superfamily
IPR044156 Galectin-likeFamilyFamily

Diseases

Show/Hide Table

Drugs

Show/Hide Table
DrugNameSourceType
DB03345 MercaptoethanolDrugbanksmall molecule
DB04396 ThiodigalactosideDrugbanksmall molecule
DB04447 1,4-DithiothreitolDrugbanksmall molecule
DB11638 ArtenimolDrugbanksmall molecule

Interactions

37 interactions

InteractorPartnerSourcesPublicationsLink
LEG1_HUMANCDC42_HUMANBioGRID, IntAct18624398 details
LEG1_HUMANPTPRC_HUMANBioGRID, HPRD, MINT10369126 10490978 details
LEG1_HUMANVGFR2_HUMANIntAct24529377 details
LEG1_HUMANCD6_HUMANMINT24945728 details
LEG1_HUMANCD166_HUMANBioGRID, IntAct, MINT24945728 28514442 details
LEG1_HUMANAP2A_HUMANIntAct24835590 details
LEG1_HUMANHSPB2_HUMANbhf-ucl, BioGRID26465331 details
LEG1_HUMANPECA1_HUMANBioGRID, IntAct28514442 32814053 details
LEG1_HUMANNLGN3_HUMANBioGRID, IntAct25464930 details
LEG1_HUMANAPOE_HUMANIntAct32814053 details
LEG1_HUMANCALR_HUMANIntAct32814053 details
LEG1_HUMANODO2_HUMANIntAct32814053 details
LEG1_HUMANNEK7_HUMANIntAct32814053 details
LEG1_HUMANUROM_HUMANIntAct32045104 details
LEG1_HUMANGEMI4_HUMANBioGRID, HPRD11522829 details
LEG1_HUMANLG3BP_HUMANBioGRID, HPRD11146440 26168351 details
LEG1_HUMANUBP4_HUMANBioGRID23022198 details
LEG1_HUMANPTEN_HUMANBioGRID26561776 details
LEG1_HUMAN1433Z_HUMANMINT15161933 details
LEG1_HUMANVGFR1_HUMANIntAct24529377 details
LEG1_HUMANMUC16_HUMANBioGRID, HPRD12615972 details
LEG1_HUMANLEG3_HUMANBioGRID11522829 details
LEG1_HUMANSMN_HUMANBioGRID11522829 details
LEG1_HUMANRSMB_HUMANBioGRID11522829 details
LEG1_HUMANGEMI2_HUMANBioGRID11522829 details
LEG1_HUMANCD2_HUMANBioGRID, HPRD10642604 details
LEG1_HUMANRASH_HUMANBioGRID, HPRD11709720 22696230 details
LEG1_HUMANLEUK_HUMANBioGRID, HPRD10490978 details
LEG1_HUMANCD7_HUMANBioGRID, HPRD10490978 details
LEG1_HUMANCD4_HUMANBioGRID, HPRD10490978 details
LEG1_HUMANEGFR_HUMANBioGRID19225046 23956138 details
LEG1_HUMANGTF2I_HUMANBioGRID18662664 details
LEG1_HUMANU2AF2_HUMANBioGRID26641092 details
LEG1_HUMANPTPRZ_HUMANBioGRID18838383 details
LEG1_HUMANSOX2_HUMANBioGRID21280222 details
LEG1_HUMANCD8A_HUMANHPRD10490978 details
LEG1_HUMANVPREB_HUMANHPRD12271131 details