Entity Details

Primary name GTR1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP11166
EntryNameGTR1_HUMAN
FullNameSolute carrier family 2, facilitated glucose transporter member 1
TaxID9606
Evidenceevidence at protein level
Length492
SequenceStatuscomplete
DateCreated1989-07-01
DateModified2021-06-02

Ontological Relatives

GenesSLC2A1

GO terms

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GOName
GO:0000139 Golgi membrane
GO:0001666 response to hypoxia
GO:0001917 photoreceptor inner segment
GO:0001939 female pronucleus
GO:0005324 long-chain fatty acid transporter activity
GO:0005355 glucose transmembrane transporter activity
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005901 caveola
GO:0005989 lactose biosynthetic process
GO:0007417 central nervous system development
GO:0007565 female pregnancy
GO:0010827 regulation of glucose transmembrane transport
GO:0014704 intercalated disc
GO:0015911 long-chain fatty acid import across plasma membrane
GO:0016020 membrane
GO:0016323 basolateral plasma membrane
GO:0016324 apical plasma membrane
GO:0019852 L-ascorbic acid metabolic process
GO:0019900 kinase binding
GO:0021987 cerebral cortex development
GO:0030018 Z disc
GO:0030496 midbody
GO:0030864 cortical actin cytoskeleton
GO:0032868 response to insulin
GO:0033300 dehydroascorbic acid transmembrane transporter activity
GO:0042149 cellular response to glucose starvation
GO:0042383 sarcolemma
GO:0042470 melanosome
GO:0042802 identical protein binding
GO:0042910 xenobiotic transmembrane transporter activity
GO:0043621 protein self-association
GO:0045494 photoreceptor cell maintenance
GO:0050796 regulation of insulin secretion
GO:0055056 D-glucose transmembrane transporter activity
GO:0065003 protein-containing complex assembly
GO:0070062 extracellular exosome
GO:0071260 cellular response to mechanical stimulus
GO:0071474 cellular hyperosmotic response
GO:0072562 blood microparticle
GO:0098708 glucose import across plasma membrane
GO:0098793 presynapse
GO:0150104 transport across blood-brain barrier
GO:1904016 response to Thyroglobulin triiodothyronine
GO:1904659 glucose transmembrane transport

Subcellular Location

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Subcellular Location
Cell membrane
Melanosome
Photoreceptor inner segment

Domains

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DomainNameCategoryType
IPR002439 Glucose transporter, type 1 (GLUT1)FamilyFamily
IPR003663 Sugar/inositol transporterFamilyFamily
IPR005828 Major facilitator, sugar transporter-likeFamilyFamily
IPR005829 Sugar transporter, conserved siteSiteConserved site
IPR020846 Major facilitator superfamily domainDomainDomain
IPR036259 MFS transporter superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00126 Ascorbic acidDrugbanksmall molecule
DB00237 ButabarbitalDrugbanksmall molecule
DB00292 EtomidateDrugbanksmall molecule
DB01914 D-glucoseSwissprotsmall molecule
DB02709 ResveratrolDrugbanksmall molecule
DB08830 Dehydroascorbic acidSwissprotsmall molecule
DB08831 2-deoxyglucoseSwissprotsmall molecule
DB09341 Dextrose, unspecified formSwissprotsmall molecule
DB09502 Fludeoxyglucose (18F)Swissprotsmall molecule
DB11059 CarboxymethylcelluloseDrugbanksmall molecule