Entity Details

Primary name CO6_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP13671
EntryNameCO6_HUMAN
FullNameComplement component C6
TaxID9606
Evidenceevidence at protein level
Length934
SequenceStatuscomplete
DateCreated1990-01-01
DateModified2021-06-02

Ontological Relatives

GenesC6

GO terms

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GOName
GO:0001701 in utero embryonic development
GO:0005576 extracellular region
GO:0005579 membrane attack complex
GO:0006956 complement activation
GO:0006958 complement activation, classical pathway
GO:0019835 cytolysis
GO:0030449 regulation of complement activation
GO:0045087 innate immune response
GO:0070062 extracellular exosome

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR000436 Sushi/SCR/CCP domainDomainDomain
IPR000884 Thrombospondin type-1 (TSP1) repeatRepeatRepeat
IPR001862 Membrane attack complex component/perforin/complement C9FamilyFamily
IPR002172 Low-density lipoprotein (LDL) receptor class A repeatRepeatRepeat
IPR002350 Kazal domainDomainDomain
IPR003884 Factor I / membrane attack complexDomainDomain
IPR020863 Membrane attack complex component/perforin domain, conserved siteSiteConserved site
IPR020864 Membrane attack complex component/perforin (MACPF) domainDomainDomain
IPR023415 Low-density lipoprotein (LDL) receptor class A, conserved siteSiteConserved site
IPR035976 Sushi/SCR/CCP superfamilyFamilyHomologous superfamily
IPR036055 LDL receptor-like superfamilyFamilyHomologous superfamily
IPR036383 Thrombospondin type-1 (TSP1) repeat superfamilyFamilyHomologous superfamily

Diseases

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