Entity Details

Primary name FPPS_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP14324
EntryNameFPPS_HUMAN
FullNameFarnesyl pyrophosphate synthase
TaxID9606
Evidenceevidence at protein level
Length419
SequenceStatuscomplete
DateCreated1990-01-01
DateModified2021-06-02

Ontological Relatives

GenesFDPS

GO terms

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GOName
GO:0003723 RNA binding
GO:0004161 dimethylallyltranstransferase activity
GO:0004337 geranyltranstransferase activity
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006695 cholesterol biosynthetic process
GO:0016032 viral process
GO:0019216 regulation of lipid metabolic process
GO:0033384 geranyl diphosphate biosynthetic process
GO:0045337 farnesyl diphosphate biosynthetic process
GO:0046872 metal ion binding

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR000092 Polyprenyl synthetaseFamilyFamily
IPR008949 Isoprenoid synthase domain superfamilyFamilyHomologous superfamily
IPR033749 Polyprenyl synthetase, conserved siteSiteConserved site

Diseases

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Drugs

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DrugNameSourceType
DB00282 Pamidronic acidDrugbanksmall molecule
DB00399 Zoledronic acidDrugbanksmall molecule
DB00630 Alendronic acidDrugbanksmall molecule
DB00710 IbandronateDrugbanksmall molecule
DB00884 Risedronic acidDrugbanksmall molecule
DB01785 Dimethylallyl DiphosphateDrugbanksmall molecule
DB02508 Isopentyl PyrophosphateDrugbanksmall molecule
DB02552 Geranyl DiphosphateDrugbanksmall molecule
DB04714 ISOPENTENYL PYROPHOSPHATEDrugbanksmall molecule
DB06255 Incadronic acidDrugbanksmall molecule
DB06548 Minodronic acidDrugbanksmall molecule
DB07780 Farnesyl diphosphateDrugbanksmall molecule
DB07841 Geranylgeranyl diphosphateDrugbanksmall molecule