Entity Details

Primary name CD19_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP15391
EntryNameCD19_HUMAN
FullNameB-lymphocyte antigen CD19
TaxID9606
Evidenceevidence at protein level
Length556
SequenceStatuscomplete
DateCreated1990-04-01
DateModified2021-06-02

Ontological Relatives

GenesCD19

GO terms

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GOName
GO:0001923 B-1 B cell differentiation
GO:0002322 B cell proliferation involved in immune response
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0009897 external side of plasma membrane
GO:0016064 immunoglobulin mediated immune response
GO:0030449 regulation of complement activation
GO:0032991 protein-containing complex
GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity
GO:0045121 membrane raft
GO:0050776 regulation of immune response
GO:0050851 antigen receptor-mediated signaling pathway
GO:0050853 B cell receptor signaling pathway
GO:0050855 regulation of B cell receptor signaling pathway
GO:0050864 regulation of B cell activation
GO:0051281 positive regulation of release of sequestered calcium ion into cytosol
GO:0051897 positive regulation of protein kinase B signaling
GO:0070062 extracellular exosome

Subcellular Location

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Subcellular Location
Cell membrane
Membrane raft

Domains

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DomainNameCategoryType
IPR003599 Immunoglobulin subtypeDomainDomain
IPR007110 Immunoglobulin-like domainDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR036179 Immunoglobulin-like domain superfamilyFamilyHomologous superfamily
IPR042341 B-lymphocyte antigen CD19FamilyFamily

Diseases

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Drugs

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DrugNameSourceType
DB06342 Coltuximab ravtansineDrugbankbiotech
DB09052 BlinatumomabDrugbankbiotech
DB12530 InebilizumabDrugbankbiotech
DB13881 TisagenlecleucelDrugbankbiotech
DB13915 Axicabtagene ciloleucelDrugbankbiotech
DB15044 TafasitamabDrugbankbiotech
DB15699 Brexucabtagene autoleucelDrugbankbiotech