Entity Details

Primary name CD1D_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP15813
EntryNameCD1D_HUMAN
FullNameAntigen-presenting glycoprotein CD1d
TaxID9606
Evidenceevidence at protein level
Length335
SequenceStatuscomplete
DateCreated1990-04-01
DateModified2021-06-02

Ontological Relatives

GenesCD1D

GO terms

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GOName
GO:0001916 positive regulation of T cell mediated cytotoxicity
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0005764 lysosome
GO:0005765 lysosomal membrane
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0009897 external side of plasma membrane
GO:0009986 cell surface
GO:0010008 endosome membrane
GO:0016045 detection of bacterium
GO:0016323 basolateral plasma membrane
GO:0030881 beta-2-microglobulin binding
GO:0030882 lipid antigen binding
GO:0030883 endogenous lipid antigen binding
GO:0030884 exogenous lipid antigen binding
GO:0034113 heterotypic cell-cell adhesion
GO:0042102 positive regulation of T cell proliferation
GO:0042393 histone binding
GO:0045058 T cell selection
GO:0045087 innate immune response
GO:0045089 positive regulation of innate immune response
GO:0048006 antigen processing and presentation, endogenous lipid antigen via MHC class Ib
GO:0048007 antigen processing and presentation, exogenous lipid antigen via MHC class Ib
GO:0050776 regulation of immune response
GO:0050839 cell adhesion molecule binding
GO:0071723 lipopeptide binding

Subcellular Location

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Subcellular Location
Basolateral cell membrane
Cell membrane
Endoplasmic reticulum membrane
Endosome membrane
Lysosome membrane

Domains

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DomainNameCategoryType
IPR003597 Immunoglobulin C1-setDomainDomain
IPR007110 Immunoglobulin-like domainDomainDomain
IPR011161 MHC class I-like antigen recognition-likeDomainDomain
IPR011162 MHC classes I/II-like antigen recognition proteinFamilyHomologous superfamily
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR036179 Immunoglobulin-like domain superfamilyFamilyHomologous superfamily
IPR037055 MHC class I-like antigen recognition-like superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB04661 cis-tetracosenoyl sulfatideDrugbanksmall molecule