Entity Details

Primary name H15_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP16401
EntryNameH15_HUMAN
FullNameHistone H1.5
TaxID9606
Evidenceevidence at protein level
Length226
SequenceStatuscomplete
DateCreated1990-08-01
DateModified2021-06-02

Ontological Relatives

GenesH1-5

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000786 nucleosome
GO:0000792 heterochromatin
GO:0003690 double-stranded DNA binding
GO:0003723 RNA binding
GO:0005634 nucleus
GO:0006325 chromatin organization
GO:0006334 nucleosome assembly
GO:0016584 nucleosome positioning
GO:0030261 chromosome condensation
GO:0030307 positive regulation of cell growth
GO:0031490 chromatin DNA binding
GO:0031492 nucleosomal DNA binding
GO:0031936 negative regulation of chromatin silencing
GO:0042826 histone deacetylase binding
GO:0045910 negative regulation of DNA recombination
GO:0050821 protein stabilization
GO:0051574 positive regulation of histone H3-K9 methylation
GO:0071169 establishment of protein localization to chromatin

Subcellular Location

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Subcellular Location
Chromosome
Nucleus

Domains

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DomainNameCategoryType
IPR005818 Linker histone H1/H5, domain H15DomainDomain
IPR005819 Linker histone H1/H5FamilyFamily
IPR036388 Winged helix-like DNA-binding domain superfamilyFamilyHomologous superfamily
IPR036390 Winged helix DNA-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

49 interactions

InteractorPartnerSourcesPublicationsLink
H15_HUMANSERPH_HUMANBioGRID11581402 details
H15_HUMANIRAK4_HUMANBioGRID15927069 details
H15_HUMANKPCA_HUMANBioGRID15927069 8663071 details
H15_HUMANCDN1B_HUMANBioGRID17671428 details
H15_HUMANCDK2_HUMANBioGRID, HPRD11259605 11980914 14612406 14681231 14701826 15169570 15514162 15607961 15670215 15753125 15800615 16191191 16205633 16762841 17671428 7629134 details
H15_HUMANCBX5_HUMANBioGRID16762841 details
H15_HUMANCDK1_HUMANBioGRID11516829 11980914 16205633 18560763 23543736 8663071 9668078 details
H15_HUMANCCNA1_HUMANBioGRID11259605 16191191 details
H15_HUMANCCNE1_HUMANBioGRID15514162 15670215 19318554 8662825 details
H15_HUMANCCNB1_HUMANBioGRID20956543 8662825 details
H15_HUMANKPCD_HUMANBioGRID11839738 15978696 details
H15_HUMANCCNA2_HUMANBioGRID15800615 8662825 details
H15_HUMANCDN1A_HUMANBioGRID8662825 details
H15_HUMANKAT2A_HUMANBioGRID10373431 details
H15_HUMANKAT2B_HUMANBioGRID10373431 details
H15_HUMANENL_HUMANBioGRID15856011 details
H15_HUMANKPCB_HUMANBioGRID8663071 details
H15_HUMANKPCZ_HUMANBioGRID8663071 details
H15_HUMANCDK5_HUMANBioGRID11516829 details
H15_HUMANNSD1_HUMANBioGRID24412544 details
H15_HUMANPARP1_HUMANBioGRID27067600 28190768 details
H15_HUMANPARP2_HUMANBioGRID28190768 details
H15_HUMANHPF1_HUMANBioGRID27067600 28190768 details
H15_HUMANRIPK3_HUMANBioGRID29883609 details
H15_HUMANCDC42_HUMANBioGRID31478661 details
H15_HUMANNPM_HUMANBioGRID, IntAct25349213 26496610 details
H15_HUMANGNA12_HUMANIntAct30021884 details
H15_HUMANGPTC8_HUMANIntAct30021884 details
H15_HUMANRRP5_HUMANIntAct30021884 details
H15_HUMANSENP3_HUMANIntAct30021884 details
H15_HUMANASCL5_HUMANIntAct30021884 details
H15_HUMANOFCC1_HUMANIntAct30021884 details
H15_HUMANH32_HUMANIntAct30021884 details
H15_HUMANTAAR3_HUMANIntAct30021884 details
H15_HUMANH4_HUMANBioGRID, IntAct30021884 30804502 details
H15_HUMANCC168_HUMANIntAct30021884 details
H15_HUMANIG2R_HUMANIntAct30021884 details
H15_HUMANH33_HUMANBioGRID17403666 details
H15_HUMANFOXP3_HUMANBioGRID21654845 details
H15_HUMANCBX6_HUMANBioGRID21282530 details
H15_HUMANZBTB1_HUMANBioGRID24657165 details
H15_HUMANH31_HUMANBioGRID23319141 details
H15_HUMANGPX7_HUMANBioGRID23123197 details
H15_HUMANMELK_HUMANHPRD16216881 details
H15_HUMANKS6A5_HUMANHPRD9873047 details
H15_HUMANSIR1_HUMANHPRD15469825 details
H15_HUMANLMBL1_HUMANHPRD17540172 details
H15_HUMANEHMT2_HUMANHPRD17540172 details
H15_HUMANLYOX_HUMANHPRD12686141 details