Entity Details

Primary name LMNB1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP20700
EntryNameLMNB1_HUMAN
FullNameLamin-B1
TaxID9606
Evidenceevidence at protein level
Length586
SequenceStatuscomplete
DateCreated1991-02-01
DateModified2021-06-02

Ontological Relatives

GenesLMNB1

GO terms

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GOName
GO:0005198 structural molecule activity
GO:0005634 nucleus
GO:0005635 nuclear envelope
GO:0005637 nuclear inner membrane
GO:0005638 lamin filament
GO:0005654 nucleoplasm
GO:0016020 membrane
GO:0016363 nuclear matrix
GO:0031965 nuclear membrane
GO:0035722 interleukin-12-mediated signaling pathway
GO:0043274 phospholipase binding
GO:1990837 sequence-specific double-stranded DNA binding

Subcellular Location

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Subcellular Location
Nucleus inner membrane

Domains

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DomainNameCategoryType
IPR001322 Lamin tail domainDomainDomain
IPR018039 Intermediate filament protein, conserved siteSiteConserved site
IPR036415 Lamin tail domain superfamilyFamilyHomologous superfamily
IPR039008 Intermediate filament, rod domainDomainDomain

Diseases

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Interactions

74 interactions

InteractorPartnerSourcesPublicationsLink
LMNB1_HUMANPASK_HUMANMINT21418524 details
LMNB1_HUMANPIAS2_HUMANBioGRID, MINT21516116 34079125 details
LMNB1_HUMANAACT_HUMANBioGRID, IntAct21988832 details
LMNB1_HUMANATF4_HUMANBioGRID, IntAct21988832 details
LMNB1_HUMANGIT2_HUMANBioGRID, IntAct21988832 details
LMNB1_HUMANMBIP1_HUMANBioGRID, IntAct21988832 details
LMNB1_HUMANABCG8_HUMANBioGRID, IntAct21988832 details
LMNB1_HUMANLMNA_HUMANBioGRID, DIP, HPRD, IntAct11792809 19727227 21346760 21988832 22412018 24623722 25948554 26264872 26524528 29568061 29997244 30021884 30419336 31467278 32814053 34079125 details
LMNB1_HUMANLMNB1_HUMANMINT22265972 details
LMNB1_HUMANLAP2B_HUMANBioGRID, IntAct26496610 34079125 8324822 9490046 details
LMNB1_HUMANIMA5_HUMANBioGRID, IntAct26496610 32296183 34079125 details
LMNB1_HUMANLMNB2_HUMANBioGRID, DIP, IntAct24981860 26524528 30021884 32296183 34079125 details
LMNB1_HUMANM1AP_HUMANBioGRID, IntAct32296183 details
LMNB1_HUMANSNAPN_HUMANBioGRID, IntAct32296183 details
LMNB1_HUMANDMAP1_HUMANBioGRID, IntAct32296183 details
LMNB1_HUMANASPP1_HUMANBioGRID, IntAct32296183 details
LMNB1_HUMANCC88B_HUMANBioGRID, IntAct32296183 details
LMNB1_HUMANCENPH_HUMANBioGRID, IntAct32296183 details
LMNB1_HUMANF169A_HUMANBioGRID, IntAct32296183 34079125 details
LMNB1_HUMANIMA7_HUMANBioGRID, IntAct32296183 details
LMNB1_HUMANPIHD2_HUMANBioGRID, IntAct32296183 details
LMNB1_HUMANMLP3B_HUMANBioGRID, DIP26524528 details
LMNB1_HUMANMLP3C_HUMANBioGRID, DIP26524528 details
LMNB1_HUMANMLP3A_HUMANBioGRID, DIP26524528 details
LMNB1_HUMANGBRAP_HUMANBioGRID, DIP26524528 details
LMNB1_HUMANKPCB_HUMANBioGRID, HPRD11901153 8034666 details
LMNB1_HUMANKPCA_HUMANBioGRID, HPRD11901153 12135703 details
LMNB1_HUMANLAP2A_HUMANBioGRID, HPRD26496610 34079125 8324822 9490046 details
LMNB1_HUMANCDK1_HUMANBioGRID, HPRD11901153 8034666 details
LMNB1_HUMANMELK_HUMANBioGRID, HPRD16216881 details
LMNB1_HUMANURB2_HUMANBioGRID, HPRD15265697 details
LMNB1_HUMAN1433T_HUMANBioGRID15161933 details
LMNB1_HUMANSRPK2_HUMANBioGRID26167880 details
LMNB1_HUMANAKTIP_HUMANBioGRID27512140 details
LMNB1_HUMANRN123_HUMANBioGRID29676528 details
LMNB1_HUMANUBC9_HUMANBioGRID32296183 details
LMNB1_HUMANASPP2_HUMANBioGRID32296183 details
LMNB1_HUMANIMA6_HUMANBioGRID32296183 details
LMNB1_HUMANPTEN_HUMANBioGRID31685992 details
LMNB1_HUMANRTCA_HUMANIntAct17353931 details
LMNB1_HUMANBCAR3_HUMANIntAct17353931 details
LMNB1_HUMANATG12_HUMANIntAct17353931 details
LMNB1_HUMANHLAB_HUMANIntAct17353931 details
LMNB1_HUMAN1433Z_HUMANMINT15161933 details
LMNB1_HUMANAIRE_HUMANBioGRID, IntAct20085707 details
LMNB1_HUMANSEP12_HUMANIntAct25775403 details
LMNB1_HUMANEMD_HUMANBioGRID12670476 17620012 34079125 details
LMNB1_HUMANVIME_HUMANBioGRID11441066 details
LMNB1_HUMANSPTN1_HUMANBioGRID11441066 details
LMNB1_HUMANNDEL1_HUMANBioGRID19198602 details
LMNB1_HUMANSMCA4_HUMANBioGRID9128241 details
LMNB1_HUMANPO2F1_HUMANBioGRID21897860 23580612 details
LMNB1_HUMANSMRCD_HUMANBioGRID21549307 details
LMNB1_HUMANRNF13_HUMANBioGRID20230530 details
LMNB1_HUMANPCGF2_HUMANBioGRID19727227 details
LMNB1_HUMANEGF_HUMANBioGRID19727227 details
LMNB1_HUMANHECW2_HUMANBioGRID24163370 29753763 details
LMNB1_HUMANSPRTN_HUMANBioGRID23254330 details
LMNB1_HUMANRAC1_HUMANBioGRID19961560 details
LMNB1_HUMANABCE1_HUMANBioGRID25659154 details
LMNB1_HUMANCTNB1_HUMANBioGRID26912724 27684187 details
LMNB1_HUMANRAD51_HUMANBioGRID28613254 details
LMNB1_HUMANST7_HUMANBioGRID29395067 details
LMNB1_HUMANEIF3H_HUMANBioGRID32269044 details
LMNB1_HUMANLBR_HUMANBioGRID, HPRD12490158 34079125 details
LMNB1_HUMANTOIP1_HUMANBioGRID, HPRD34079125 9305626 details
LMNB1_HUMANSUMO4_HUMANHPRD16236267 details
LMNB1_HUMANGRAB_HUMANHPRD11331782 details
LMNB1_HUMANGRAA_HUMANHPRD11331782 details
LMNB1_HUMANPERI_HUMANHPRD1986862 details
LMNB1_HUMANKPCD_HUMANHPRD11901153 details
LMNB1_HUMANCASP3_HUMANHPRD11901153 details
LMNB1_HUMANPLEC_HUMANHPRD2023931 details
LMNB1_HUMANCASP6_HUMANHPRD11331782 11901153 details