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Entity Details
Primary name
ICAL_HUMAN
Entity type
UniProt
Source
Source Link
Details
Accession
P20810
EntryName
ICAL_HUMAN
FullName
Calpastatin
TaxID
9606
Evidence
evidence at protein level
Length
708
SequenceStatus
complete
DateCreated
1991-02-01
DateModified
2021-06-02
Ontological Relatives
Genes
CAST
GO terms
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GO
Name
GO:0003723
RNA binding
GO:0004866
endopeptidase inhibitor activity
GO:0005737
cytoplasm
GO:0005783
endoplasmic reticulum
GO:0005829
cytosol
GO:0010859
calcium-dependent cysteine-type endopeptidase inhibitor activity
GO:0016020
membrane
GO:0045296
cadherin binding
GO:0097340
inhibition of cysteine-type endopeptidase activity
GO:1990709
presynaptic active zone organization
GO:2000675
negative regulation of type B pancreatic cell apoptotic process
Subcellular Location
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Domains
Show/Hide Table
Domain
Name
Category
Type
IPR001259
Proteinase inhibitor I27, calpastatin
Repeat
Repeat
IPR026998
Calpastatin
Family
Family
Diseases
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Drugs
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Drug
Name
Source
Type
DB01373
Calcium
Drugbank
small molecule
DB11638
Artenimol
Drugbank
small molecule
Interactions
20 interactions
Interactor
Partner
Sources
Publications
Link
ICAL_HUMAN
ABL1_HUMAN
IntAct
17474147
details
ICAL_HUMAN
CRK_HUMAN
BioGRID, IntAct
17474147
26344197
details
ICAL_HUMAN
SRC_HUMAN
IntAct
17474147
details
ICAL_HUMAN
FYN_HUMAN
IntAct
17474147
details
ICAL_HUMAN
GRB2_HUMAN
IntAct
17474147
details
ICAL_HUMAN
NCK1_HUMAN
IntAct
17474147
details
ICAL_HUMAN
P85A_HUMAN
IntAct
17474147
details
ICAL_HUMAN
PLCG1_HUMAN
IntAct
17474147
details
ICAL_HUMAN
SUMO2_HUMAN
BioGRID
32786267
details
ICAL_HUMAN
LIPA1_HUMAN
HPRD
12923177
details
ICAL_HUMAN
LIPA2_HUMAN
HPRD
12923177
details
ICAL_HUMAN
LIPA3_HUMAN
HPRD
12923177
details
ICAL_HUMAN
HTRA1_HUMAN
HPRD
15101818
details
ICAL_HUMAN
CAN1_HUMAN
BioGRID, HPRD, IntAct
12684003
20679491
26496610
28514442
details
ICAL_HUMAN
NUCL_HUMAN
IntAct
30021884
details
ICAL_HUMAN
CPNS1_HUMAN
HPRD, IntAct
12684003
28319173
details
ICAL_HUMAN
PAF15_HUMAN
BioGRID
21263028
details
ICAL_HUMAN
CASP3_HUMAN
HPRD
9705209
details
ICAL_HUMAN
CASP7_HUMAN
HPRD
10731697
details
ICAL_HUMAN
CASP1_HUMAN
HPRD
9705209
details
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