Entity Details

Primary name GPX3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP22352
EntryNameGPX3_HUMAN
FullNameGlutathione peroxidase 3
TaxID9606
Evidenceevidence at protein level
Length226
SequenceStatuscomplete
DateCreated1991-08-01
DateModified2021-06-02

Ontological Relatives

GenesGPX3

GO terms

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GOName
GO:0004601 peroxidase activity
GO:0004602 glutathione peroxidase activity
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0006982 response to lipid hydroperoxide
GO:0008134 transcription factor binding
GO:0008430 selenium binding
GO:0034599 cellular response to oxidative stress
GO:0042744 hydrogen peroxide catabolic process
GO:0042802 identical protein binding
GO:0070062 extracellular exosome

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR000889 Glutathione peroxidaseFamilyFamily
IPR029759 Glutathione peroxidase active siteSiteActive site
IPR029760 Glutathione peroxidase conserved siteSiteConserved site
IPR036249 Thioredoxin-like superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00143 GlutathioneDrugbanksmall molecule
DB03310 Glutathione disulfideDrugbanksmall molecule

Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
GPX3_HUMANUBQL1_HUMANBioGRID, IntAct25416956 details
GPX3_HUMANQORX_HUMANBioGRID22461624 details
GPX3_HUMANGPX3_HUMANBioGRID3693360 details