Entity Details

Primary name CRYGS_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP22914
EntryNameCRYGS_HUMAN
FullNameGamma-crystallin S
TaxID9606
Evidenceevidence at protein level
Length178
SequenceStatuscomplete
DateCreated1991-08-01
DateModified2021-06-02

Ontological Relatives

GenesCRYGS

GO terms

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GOName
GO:0002009 morphogenesis of an epithelium
GO:0002088 lens development in camera-type eye
GO:0005212 structural constituent of eye lens
GO:0007601 visual perception

Subcellular Location

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Domains

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DomainNameCategoryType
IPR001064 Beta/gamma crystallinDomainDomain
IPR011024 Gamma-crystallin-likeFamilyHomologous superfamily

Diseases

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Disease IDSourceNameDescription
116100 OMIMCataract 20, multiple types (CTRCT20)An opacification of the crystalline lens of the eye that frequently results in visual impairment or blindness. Opacities vary in morphology, are often confined to a portion of the lens, and may be static or progressive. In general, the more posteriorly located and dense an opacity, the greater the impact on visual function. CTRCT20 includes progressive polymorphic anterior, posterior, or peripheral cortical. The disease is caused by variants affecting the gene represented in this entry.

Interactions

4 interactions

InteractorPartnerSourcesPublicationsLink
CRYGS_HUMANTE2IP_HUMANbhf-ucl, BioGRID21044950 details
CRYGS_HUMANTINF2_HUMANbhf-ucl, BioGRID21044950 details
CRYGS_HUMANPOTE1_HUMANbhf-ucl, BioGRID21044950 details
CRYGS_HUMANCRYAB_HUMANBioGRID, DIP24183572 details