Entity Details

Primary name RS3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP23396
EntryNameRS3_HUMAN
FullName40S ribosomal protein S3
TaxID9606
Evidenceevidence at protein level
Length243
SequenceStatuscomplete
DateCreated1991-11-01
DateModified2021-06-02

Ontological Relatives

GenesRPS3

GO terms

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GOName
GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0002181 cytoplasmic translation
GO:0003677 DNA binding
GO:0003684 damaged DNA binding
GO:0003723 RNA binding
GO:0003729 mRNA binding
GO:0003735 structural constituent of ribosome
GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity
GO:0004520 endodeoxyribonuclease activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005743 mitochondrial inner membrane
GO:0005759 mitochondrial matrix
GO:0005783 endoplasmic reticulum
GO:0005829 cytosol
GO:0005840 ribosome
GO:0005844 polysome
GO:0005886 plasma membrane
GO:0005925 focal adhesion
GO:0006281 DNA repair
GO:0006412 translation
GO:0006413 translational initiation
GO:0006614 SRP-dependent cotranslational protein targeting to membrane
GO:0006915 apoptotic process
GO:0006974 cellular response to DNA damage stimulus
GO:0007059 chromosome segregation
GO:0008017 microtubule binding
GO:0008134 transcription factor binding
GO:0010628 positive regulation of gene expression
GO:0014069 postsynaptic density
GO:0015631 tubulin binding
GO:0016020 membrane
GO:0017148 negative regulation of translation
GO:0019083 viral transcription
GO:0019899 enzyme binding
GO:0019900 kinase binding
GO:0019901 protein kinase binding
GO:0022626 cytosolic ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:0030544 Hsp70 protein binding
GO:0031116 positive regulation of microtubule polymerization
GO:0031334 positive regulation of protein-containing complex assembly
GO:0031397 negative regulation of protein ubiquitination
GO:0032079 positive regulation of endodeoxyribonuclease activity
GO:0032357 oxidized purine DNA binding
GO:0032358 oxidized pyrimidine DNA binding
GO:0032587 ruffle membrane
GO:0032743 positive regulation of interleukin-2 production
GO:0034614 cellular response to reactive oxygen species
GO:0042104 positive regulation of activated T cell proliferation
GO:0042769 DNA damage response, detection of DNA damage
GO:0042981 regulation of apoptotic process
GO:0043507 positive regulation of JUN kinase activity
GO:0044390 ubiquitin-like protein conjugating enzyme binding
GO:0044877 protein-containing complex binding
GO:0045738 negative regulation of DNA repair
GO:0045739 positive regulation of DNA repair
GO:0050862 positive regulation of T cell receptor signaling pathway
GO:0051018 protein kinase A binding
GO:0051092 positive regulation of NF-kappaB transcription factor activity
GO:0051225 spindle assembly
GO:0051301 cell division
GO:0051536 iron-sulfur cluster binding
GO:0051879 Hsp90 protein binding
GO:0061481 response to TNF agonist
GO:0070062 extracellular exosome
GO:0070181 small ribosomal subunit rRNA binding
GO:0070301 cellular response to hydrogen peroxide
GO:0071159 NF-kappaB complex
GO:0071356 cellular response to tumor necrosis factor
GO:0072686 mitotic spindle
GO:0097100 supercoiled DNA binding
GO:0140078 class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GO:1901224 positive regulation of NIK/NF-kappaB signaling
GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage
GO:1902546 positive regulation of DNA N-glycosylase activity
GO:1905053 positive regulation of base-excision repair
GO:1990904 ribonucleoprotein complex
GO:2001235 positive regulation of apoptotic signaling pathway
GO:2001272 positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis

Subcellular Location

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Subcellular Location
Cytoplasm
Mitochondrion inner membrane
Nucleus

Domains

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DomainNameCategoryType
IPR001351 Ribosomal protein S3, C-terminalDomainDomain
IPR004044 K Homology domain, type 2DomainDomain
IPR005703 Ribosomal protein S3, eukaryotic/archaealFamilyFamily
IPR009019 K homology domain superfamily, prokaryotic typeFamilyHomologous superfamily
IPR015946 K homology domain-like, alpha/betaFamilyHomologous superfamily
IPR018280 Ribosomal protein S3, conserved siteSiteConserved site
IPR036419 Ribosomal protein S3, C-terminal domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

62 interactions

InteractorPartnerSourcesPublicationsLink
RS3_HUMANRL9_HUMANBioGRID, HPRD, IntAct16169070 22939629 26344197 details
RS3_HUMANIKKB_HUMANInnateDB21399639 details
RS3_HUMANFOLH1_HUMANBioGRID, IntAct21988832 details
RS3_HUMANVA0D2_HUMANBioGRID, IntAct21988832 details
RS3_HUMANCSK21_HUMANBioGRID, IntAct22113938 23188828 details
RS3_HUMANPPID_HUMANBioGRID, UniProt21146485 details
RS3_HUMANMDM2_HUMANBioGRID, IntAct19656744 details
RS3_HUMANP53_HUMANBioGRID, IntAct19656744 31152661 details
RS3_HUMANLRRK2_HUMANIntAct24725412 31046837 details
RS3_HUMANDUX4_HUMANBioGRID, IntAct26816005 details
RS3_HUMANLTV1_HUMANBioGRID, IntAct32296183 details
RS3_HUMANHD_HUMANIntAct32814053 details
RS3_HUMANHS90A_HUMANBioGRID16314389 details
RS3_HUMAN1433T_HUMANBioGRID15161933 20618440 details
RS3_HUMANSUMO1_HUMANBioGRID21968017 details
RS3_HUMANRS4X_HUMANBioGRID22863883 22939629 26344197 6188845 details
RS3_HUMANTCPB_HUMANBioGRID23190606 details
RS3_HUMANTRAF2_HUMANBioGRID23188828 details
RS3_HUMANPTEN_HUMANBioGRID26561776 details
RS3_HUMANUBC_HUMANBioGRID28190767 details
RS3_HUMANWBP2_HUMANBioGRID27578003 details
RS3_HUMANDDIT3_HUMANBioGRID29371697 details
RS3_HUMANSUMO2_HUMANBioGRID32786267 details
RS3_HUMANOGT1_HUMANBioGRID32994395 details
RS3_HUMANNEMO_HUMANIntAct14743216 details
RS3_HUMANNFKB2_HUMANIntAct14743216 details
RS3_HUMANM3K14_HUMANIntAct14743216 details
RS3_HUMANTF65_HUMANBioGRID, HPRD, IntAct, MINT14743216 18045535 23188828 24457201 26526615 details
RS3_HUMANM3K7_HUMANIntAct14743216 details
RS3_HUMANTNR1A_HUMANIntAct14743216 details
RS3_HUMANTNR1B_HUMANIntAct14743216 details
RS3_HUMANTRADD_HUMANIntAct14743216 details
RS3_HUMANTRAF1_HUMANIntAct14743216 details
RS3_HUMAN1433Z_HUMANMINT15161933 20618440 details
RS3_HUMANNFKB1_HUMANBioGRID, HPRD, IntAct, MINT18045535 23188828 25609649 details
RS3_HUMANIKBA_HUMANBioGRID, IntAct, MINT18045535 24457201 32555320 details
RS3_HUMANNEDD8_HUMANBioGRID, IntAct, MINT18274552 21145461 details
RS3_HUMANDDX3X_HUMANBioGRID, UniProt22323517 22863883 details
RS3_HUMANRL26_HUMANBioGRID, UniProt22323517 26344197 30626644 details
RS3_HUMANRS2_HUMANBioGRID, IntAct22863883 22939629 23612971 26186194 26344197 28514442 details
RS3_HUMANHSP74_HUMANBioGRID16314389 details
RS3_HUMANCAF1A_HUMANBioGRID21209461 details
RS3_HUMANCK5P3_HUMANBioGRID20164180 details
RS3_HUMANHDAC5_HUMANBioGRID21081666 details
RS3_HUMANRBM39_HUMANBioGRID16051665 28302793 details
RS3_HUMANVHL_HUMANBioGRID21942715 23612971 details
RS3_HUMANPARD3_HUMANBioGRID18685789 details
RS3_HUMAN2AAA_HUMANBioGRID18172692 23443559 details
RS3_HUMANTRI18_HUMANBioGRID18172692 details
RS3_HUMANTXN4B_HUMANBioGRID21048991 details
RS3_HUMANUBXN6_HUMANBioGRID22337587 details
RS3_HUMANITA4_HUMANBioGRID22623428 details
RS3_HUMANGAN_HUMANBioGRID26460568 details
RS3_HUMANBRE1A_HUMANBioGRID27557628 details
RS3_HUMANRN169_HUMANBioGRID28325877 details
RS3_HUMANASCC3_HUMANBioGRID28757607 details
RS3_HUMANACLY_HUMANBioGRID27664236 details
RS3_HUMANRN138_HUMANBioGRID29371697 details
RS3_HUMANSOX2_HUMANBioGRID21280222 details
RS3_HUMANANR55_HUMANBioGRID31620119 details
RS3_HUMANLXN_HUMANBioGRID32555320 details
RS3_HUMANHECD1_HUMANBioGRID32555320 details