Entity Details

Primary name ITA3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP26006
EntryNameITA3_HUMAN
FullNameIntegrin alpha-3
TaxID9606
Evidenceevidence at protein level
Length1051
SequenceStatuscomplete
DateCreated1992-05-01
DateModified2021-06-02

Ontological Relatives

GenesITGA3

GO terms

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GOName
GO:0001764 neuron migration
GO:0001968 fibronectin binding
GO:0002020 protease binding
GO:0005178 integrin binding
GO:0005518 collagen binding
GO:0005886 plasma membrane
GO:0005925 focal adhesion
GO:0007160 cell-matrix adhesion
GO:0007229 integrin-mediated signaling pathway
GO:0007507 heart development
GO:0007613 memory
GO:0008305 integrin complex
GO:0009897 external side of plasma membrane
GO:0009986 cell surface
GO:0010628 positive regulation of gene expression
GO:0010634 positive regulation of epithelial cell migration
GO:0010811 positive regulation of cell-substrate adhesion
GO:0010976 positive regulation of neuron projection development
GO:0016323 basolateral plasma membrane
GO:0017015 regulation of transforming growth factor beta receptor signaling pathway
GO:0019904 protein domain specific binding
GO:0030111 regulation of Wnt signaling pathway
GO:0030198 extracellular matrix organization
GO:0030324 lung development
GO:0030510 regulation of BMP signaling pathway
GO:0031345 negative regulation of cell projection organization
GO:0031527 filopodium membrane
GO:0034667 integrin alpha3-beta1 complex
GO:0034698 response to gonadotropin
GO:0035024 negative regulation of Rho protein signal transduction
GO:0035640 exploration behavior
GO:0042493 response to drug
GO:0043235 receptor complex
GO:0043236 laminin binding
GO:0043588 skin development
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity
GO:0048333 mesodermal cell differentiation
GO:0048471 perinuclear region of cytoplasm
GO:0050900 leukocyte migration
GO:0060076 excitatory synapse
GO:0060135 maternal process involved in female pregnancy
GO:0070062 extracellular exosome
GO:0071944 cell periphery
GO:0072006 nephron development
GO:0097060 synaptic membrane
GO:0097062 dendritic spine maintenance
GO:0097205 renal filtration
GO:1903078 positive regulation of protein localization to plasma membrane
GO:1990812 growth cone filopodium

Subcellular Location

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Subcellular Location
Cell membrane
Cell projection

Domains

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DomainNameCategoryType
IPR000413 Integrin alpha chainFamilyFamily
IPR013517 FG-GAP repeatRepeatRepeat
IPR013519 Integrin alpha beta-propellorRepeatRepeat
IPR013649 Integrin alpha-2DomainDomain
IPR018184 Integrin alpha chain, C-terminal cytoplasmic region, conserved siteSiteConserved site
IPR028994 Integrin alpha, N-terminalFamilyHomologous superfamily
IPR032695 Integrin domain superfamilyFamilyHomologous superfamily

Diseases

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