Entity Details

Primary name PTX3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP26022
EntryNamePTX3_HUMAN
FullNamePentraxin-related protein PTX3
TaxID9606
Evidenceevidence at protein level
Length381
SequenceStatuscomplete
DateCreated1992-05-01
DateModified2021-06-02

Ontological Relatives

GenesPTX3

GO terms

Show/Hide Table
GOName
GO:0001550 ovarian cumulus expansion
GO:0001849 complement component C1q complex binding
GO:0001872 (1->3)-beta-D-glucan binding
GO:0001878 response to yeast
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0006954 inflammatory response
GO:0008228 opsonization
GO:0030198 extracellular matrix organization
GO:0031012 extracellular matrix
GO:0035580 specific granule lumen
GO:0042802 identical protein binding
GO:0043312 neutrophil degranulation
GO:0044793 negative regulation by host of viral process
GO:0044869 negative regulation by host of viral exo-alpha-sialidase activity
GO:0044871 negative regulation by host of viral glycoprotein metabolic process
GO:0045087 innate immune response
GO:0045429 positive regulation of nitric oxide biosynthetic process
GO:0046597 negative regulation of viral entry into host cell
GO:0046790 virion binding
GO:0050766 positive regulation of phagocytosis
GO:1903016 negative regulation of exo-alpha-sialidase activity
GO:1903019 negative regulation of glycoprotein metabolic process
GO:1904724 tertiary granule lumen

Subcellular Location

Show/Hide Table
Subcellular Location
Secreted

Domains

Show/Hide Table
DomainNameCategoryType
IPR001759 Pentraxin-relatedFamilyFamily
IPR006558 LamG-like jellyroll foldDomainDomain
IPR013320 Concanavalin A-like lectin/glucanase domain superfamilyFamilyHomologous superfamily
IPR030476 Pentaxin, conserved siteSiteConserved site
IPR042837 Pentraxin-related protein PTX3FamilyFamily

Diseases

Show/Hide Table