Entity Details

Primary name SSR2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP30874
EntryNameSSR2_HUMAN
FullNameSomatostatin receptor type 2
TaxID9606
Evidenceevidence at protein level
Length369
SequenceStatuscomplete
DateCreated1993-07-01
DateModified2021-06-02

Ontological Relatives

GenesSSTR2

GO terms

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GOName
GO:0004930 G protein-coupled receptor activity
GO:0004994 somatostatin receptor activity
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006937 regulation of muscle contraction
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007187 G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway
GO:0007218 neuropeptide signaling pathway
GO:0007283 spermatogenesis
GO:0008285 negative regulation of cell population proliferation
GO:0021549 cerebellum development
GO:0030165 PDZ domain binding
GO:0030432 peristalsis
GO:0030900 forebrain development
GO:0042277 peptide binding
GO:0042594 response to starvation
GO:0042923 neuropeptide binding
GO:0043005 neuron projection
GO:0071385 cellular response to glucocorticoid stimulus
GO:0071392 cellular response to estradiol stimulus

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasm

Domains

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DomainNameCategoryType
IPR000276 G protein-coupled receptor, rhodopsin-likeFamilyFamily
IPR000586 Somatostatin receptor familyFamilyFamily
IPR002074 Somatostatin receptor 2FamilyFamily
IPR017452 GPCR, rhodopsin-like, 7TMDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB04894 VapreotideDrugbanksmall molecule
DB06663 PasireotideDrugbanksmall molecule
DB06791 LanreotideDrugbanksmall molecule
DB09099 SomatostatinDrugbanksmall molecule
DB13925 Dotatate gallium Ga-68Drugbanksmall molecule
DB13985 Lutetium Lu 177 dotatateDrugbanksmall molecule
DB15494 Edotreotide gallium Ga-68Drugbanksmall molecule
DB15873 Copper oxodotreotide Cu-64Drugbanksmall molecule