Entity Details

Primary name SDHA_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP31040
EntryNameSDHA_HUMAN
FullNameSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial
TaxID9606
Evidenceevidence at protein level
Length664
SequenceStatuscomplete
DateCreated1993-07-01
DateModified2021-06-02

Ontological Relatives

GenesSDHA

GO terms

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GOName
GO:0005730 nucleolus
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005749 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)
GO:0006099 tricarboxylic acid cycle
GO:0006105 succinate metabolic process
GO:0006121 mitochondrial electron transport, succinate to ubiquinone
GO:0007399 nervous system development
GO:0008177 succinate dehydrogenase (ubiquinone) activity
GO:0009055 electron transfer activity
GO:0022904 respiratory electron transport chain
GO:0050660 flavin adenine dinucleotide binding

Subcellular Location

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Subcellular Location
Mitochondrion inner membrane

Domains

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DomainNameCategoryType
IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding siteSiteBinding site
IPR003953 FAD-dependent oxidoreductase 2, FAD binding domainDomainDomain
IPR011281 Succinate dehydrogenase, flavoprotein subunitFamilyFamily
IPR014006 Succinate dehydrogenase/fumarate reductase, flavoprotein subunitFamilyFamily
IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminalDomainDomain
IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamilyFamilyHomologous superfamily
IPR036188 FAD/NAD(P)-binding domain superfamilyFamilyHomologous superfamily
IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00139 Succinic acidDrugbanksmall molecule
DB04141 2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-TriolDrugbanksmall molecule
DB04657 CarboxinDrugbanksmall molecule
DB04795 ThenoyltrifluoroacetoneDrugbanksmall molecule
DB08689 Ubiquinone Q1Drugbanksmall molecule
DB09270 UbidecarenoneDrugbanksmall molecule