Entity Details

Primary name 5HT7R_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP34969
EntryName5HT7R_HUMAN
FullName5-hydroxytryptamine receptor 7
TaxID9606
Evidenceevidence at protein level
Length479
SequenceStatuscomplete
DateCreated1994-02-01
DateModified2021-06-02

Ontological Relatives

GenesHTR7

GO terms

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GOName
GO:0002862 negative regulation of inflammatory response to antigenic stimulus
GO:0004993 G protein-coupled serotonin receptor activity
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006939 smooth muscle contraction
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007187 G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
GO:0007268 chemical synaptic transmission
GO:0007623 circadian rhythm
GO:0008015 blood circulation
GO:0030425 dendrite
GO:0030594 neurotransmitter receptor activity
GO:0032588 trans-Golgi network membrane
GO:0042310 vasoconstriction
GO:0045202 synapse

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000276 G protein-coupled receptor, rhodopsin-likeFamilyFamily
IPR001069 5-Hydroxytryptamine 7 receptorFamilyFamily
IPR017452 GPCR, rhodopsin-like, 7TMDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB00246 ZiprasidoneDrugbanksmall molecule
DB00247 MethysergideDrugbanksmall molecule
DB00248 CabergolineDrugbanksmall molecule
DB00315 ZolmitriptanDrugbanksmall molecule
DB00321 AmitriptylineDrugbanksmall molecule
DB00363 ClozapineDrugbanksmall molecule
DB00408 LoxapineDrugbanksmall molecule
DB00434 CyproheptadineDrugbanksmall molecule
DB00458 ImipramineDrugbanksmall molecule
DB00477 ChlorpromazineDrugbanksmall molecule
DB00502 HaloperidolDrugbanksmall molecule
DB00543 AmoxapineDrugbanksmall molecule
DB00589 LisurideDrugbanksmall molecule
DB00715 ParoxetineDrugbanksmall molecule
DB00734 RisperidoneDrugbanksmall molecule
DB00751 EpinastineDrugbanksmall molecule
DB00924 CyclobenzaprineDrugbanksmall molecule
DB00934 MaprotilineDrugbanksmall molecule
DB00988 DopamineDrugbanksmall molecule
DB01049 Ergoloid mesylateDrugbanksmall molecule
DB01200 BromocriptineDrugbanksmall molecule
DB01224 QuetiapineDrugbanksmall molecule
DB01238 AripiprazoleDrugbanksmall molecule
DB01239 ChlorprothixeneDrugbanksmall molecule
DB01267 PaliperidoneDrugbanksmall molecule
DB04946 IloperidoneDrugbanksmall molecule
DB04948 LofexidineDrugbanksmall molecule
DB06148 MianserinDrugbanksmall molecule
DB06216 AsenapineDrugbanksmall molecule
DB06288 AmisulprideDrugbanksmall molecule
DB08815 LurasidoneDrugbanksmall molecule
DB09068 VortioxetineDrugbanksmall molecule
DB09225 ZotepineDrugbanksmall molecule
DB09304 SetiptilineDrugbanksmall molecule
DB11273 DihydroergocornineDrugbanksmall molecule
DB12141 GilteritinibDrugbanksmall molecule
DB13025 TiaprideDrugbanksmall molecule
DB13345 DihydroergocristineDrugbanksmall molecule
DB13988 SB-269970Drugbanksmall molecule
DB14185 Aripiprazole lauroxilDrugbanksmall molecule

Interactions

4 interactions

InteractorPartnerSourcesPublicationsLink
5HT7R_HUMANGASP1_HUMANBioGRID, IntAct15086532 details
5HT7R_HUMANGASP2_HUMANBioGRID, HPRD, IntAct15086532 details
5HT7R_HUMANRHBT3_HUMANBioGRID22245496 details
5HT7R_HUMANCUL3_HUMANBioGRID22245496 details