Entity Details

Primary name TSP4_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP35443
EntryNameTSP4_HUMAN
FullNameThrombospondin-4
TaxID9606
Evidenceevidence at protein level
Length961
SequenceStatuscomplete
DateCreated1994-06-01
DateModified2021-06-02

Ontological Relatives

GenesTHBS4

GO terms

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GOName
GO:0001938 positive regulation of endothelial cell proliferation
GO:0005178 integrin binding
GO:0005509 calcium ion binding
GO:0005576 extracellular region
GO:0005604 basement membrane
GO:0005615 extracellular space
GO:0005783 endoplasmic reticulum
GO:0006986 response to unfolded protein
GO:0008083 growth factor activity
GO:0008201 heparin binding
GO:0016525 negative regulation of angiogenesis
GO:0016529 sarcoplasmic reticulum
GO:0034103 regulation of tissue remodeling
GO:0034976 response to endoplasmic reticulum stress
GO:0048266 behavioral response to pain
GO:0048771 tissue remodeling
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
GO:0051451 myoblast migration
GO:0051781 positive regulation of cell division
GO:0062023 collagen-containing extracellular matrix
GO:0070062 extracellular exosome
GO:0071603 endothelial cell-cell adhesion
GO:0090023 positive regulation of neutrophil chemotaxis

Subcellular Location

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Subcellular Location
Endoplasmic reticulum
Sarcoplasmic reticulum
Secreted

Domains

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DomainNameCategoryType
IPR000742 EGF-like domainDomainDomain
IPR001791 Laminin G domainDomainDomain
IPR001881 EGF-like calcium-binding domainDomainDomain
IPR003367 Thrombospondin, type 3-like repeatRepeatRepeat
IPR008859 Thrombospondin, C-terminalDomainDomain
IPR013320 Concanavalin A-like lectin/glucanase domain superfamilyFamilyHomologous superfamily
IPR017897 Thrombospondin, type 3 repeatRepeatRepeat
IPR018097 EGF-like calcium-binding, conserved siteSiteConserved site
IPR024665 Thrombospondin/cartilage oligomeric matrix protein, coiled-coil domainDomainDomain
IPR028974 TSP type-3 repeatFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
TSP4_HUMANA4_HUMANBioGRID21244100 details