Entity Details

Primary name TCF7_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP36402
EntryNameTCF7_HUMAN
FullNameTranscription factor 7
TaxID9606
Evidenceevidence at protein level
Length384
SequenceStatuscomplete
DateCreated1994-06-01
DateModified2021-06-02

Ontological Relatives

GenesTCF7

GO terms

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GOName
GO:0000976 transcription cis-regulatory region binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001217 DNA-binding transcription repressor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006955 immune response
GO:0008013 beta-catenin binding
GO:0016604 nuclear body
GO:0033153 T cell receptor V(D)J recombination
GO:0042492 gamma-delta T cell differentiation
GO:0045586 regulation of gamma-delta T cell differentiation
GO:0060070 canonical Wnt signaling pathway
GO:0071353 cellular response to interleukin-4
GO:1904837 beta-catenin-TCF complex assembly
GO:1990837 sequence-specific double-stranded DNA binding
GO:1990907 beta-catenin-TCF complex

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR009071 High mobility group box domainDomainDomain
IPR013558 CTNNB1 binding, N-teminalDomainDomain
IPR024940 Transcription factor TCF/LEFFamilyFamily
IPR027397 Catenin binding domain superfamilyFamilyHomologous superfamily
IPR028785 Transcription factor 7FamilyFamily
IPR036910 High mobility group box domain superfamilyFamilyHomologous superfamily

Diseases

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