Entity Details

Primary name ARL2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP36404
EntryNameARL2_HUMAN
FullNameADP-ribosylation factor-like protein 2
TaxID9606
Evidenceevidence at protein level
Length184
SequenceStatuscomplete
DateCreated1994-06-01
DateModified2021-06-02

Ontological Relatives

GenesARL2

GO terms

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GOName
GO:0000165 MAPK cascade
GO:0003924 GTPase activity
GO:0005095 GTPase inhibitor activity
GO:0005525 GTP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005758 mitochondrial intermembrane space
GO:0005759 mitochondrial matrix
GO:0005794 Golgi apparatus
GO:0005813 centrosome
GO:0005829 cytosol
GO:0005925 focal adhesion
GO:0007021 tubulin complex assembly
GO:0007098 centrosome cycle
GO:0010811 positive regulation of cell-substrate adhesion
GO:0015630 microtubule cytoskeleton
GO:0016328 lateral plasma membrane
GO:0019003 GDP binding
GO:0031113 regulation of microtubule polymerization
GO:0031116 positive regulation of microtubule polymerization
GO:0034260 negative regulation of GTPase activity
GO:0051457 maintenance of protein location in nucleus
GO:0070830 bicellular tight junction assembly

Subcellular Location

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Subcellular Location
Cytoplasm
Mitochondrion intermembrane space
Nucleus

Domains

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DomainNameCategoryType
IPR005225 Small GTP-binding protein domainDomainDomain
IPR006689 Small GTPase superfamily, ARF/SAR typeFamilyFamily
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR044612 ADP-ribosylation factor-like protein 2/3FamilyFamily

Diseases

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Drugs

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DrugNameSourceType
DB14731 TagraxofuspDrugbankbiotech