Entity Details

Primary name SMBP2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP38935
EntryNameSMBP2_HUMAN
FullNameDNA-binding protein SMUBP-2
TaxID9606
Evidenceevidence at protein level
Length993
SequenceStatuscomplete
DateCreated1995-02-01
DateModified2021-06-02

Ontological Relatives

GenesIGHMBP2

GO terms

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GOName
GO:0000049 tRNA binding
GO:0003677 DNA binding
GO:0003678 DNA helicase activity
GO:0003697 single-stranded DNA binding
GO:0003723 RNA binding
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0006260 DNA replication
GO:0006281 DNA repair
GO:0006310 DNA recombination
GO:0006412 translation
GO:0008094 ATPase, acting on DNA
GO:0008134 transcription factor binding
GO:0008186 ATPase, acting on RNA
GO:0008270 zinc ion binding
GO:0016020 membrane
GO:0016604 nuclear body
GO:0030424 axon
GO:0030426 growth cone
GO:0032574 5'-3' RNA helicase activity
GO:0042802 identical protein binding
GO:0043022 ribosome binding
GO:0043139 5'-3' DNA helicase activity
GO:1990904 ribonucleoprotein complex

Subcellular Location

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Subcellular Location
Cell projection
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000058 Zinc finger, AN1-typeDomainDomain
IPR001374 R3H domainDomainDomain
IPR003593 AAA+ ATPase domainDomainDomain
IPR004483 Helicase SMUBP-2/Hcs1-likeFamilyFamily
IPR014001 Helicase superfamily 1/2, ATP-binding domainDomainDomain
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR034072 DNA-binding protein SMUBP-2, R3H domainDomainDomain
IPR035896 AN1-like Zinc fingerFamilyHomologous superfamily
IPR036867 R3H domain superfamilyFamilyHomologous superfamily
IPR041677 DNA2/NAM7 helicase, helicase domainDomainDomain
IPR041679 DNA2/NAM7 helicase-like, C-terminalDomainDomain

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
SMBP2_HUMANLSM8_HUMANBioGRID, HPRD, IntAct15231747 details
SMBP2_HUMANDISC1_HUMANIntAct31413325 details