Entity Details

Primary name RFC5_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP40937
EntryNameRFC5_HUMAN
FullNameReplication factor C subunit 5
TaxID9606
Evidenceevidence at protein level
Length340
SequenceStatuscomplete
DateCreated1995-02-01
DateModified2021-06-02

Ontological Relatives

GenesRFC5

GO terms

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GOName
GO:0003677 DNA binding
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005663 DNA replication factor C complex
GO:0006260 DNA replication
GO:0006261 DNA-dependent DNA replication
GO:0006281 DNA repair
GO:0006283 transcription-coupled nucleotide-excision repair
GO:0006287 base-excision repair, gap-filling
GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion
GO:0006297 nucleotide-excision repair, DNA gap filling
GO:0016887 ATP hydrolysis activity
GO:0019899 enzyme binding
GO:0019985 translesion synthesis
GO:0031390 Ctf18 RFC-like complex
GO:0032201 telomere maintenance via semi-conservative replication
GO:0032508 DNA duplex unwinding
GO:0033683 nucleotide-excision repair, DNA incision
GO:0042276 error-prone translesion synthesis
GO:0042769 DNA damage response, detection of DNA damage
GO:0070987 error-free translesion synthesis
GO:1900264 positive regulation of DNA-directed DNA polymerase activity
GO:1901796 regulation of signal transduction by p53 class mediator

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR003593 AAA+ ATPase domainDomainDomain
IPR003959 ATPase, AAA-type, coreDomainDomain
IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminalFamilyHomologous superfamily
IPR013748 Replication factor C, C-terminalDomainDomain
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily

Diseases

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Interactions

52 interactions

InteractorPartnerSourcesPublicationsLink
RFC5_HUMANCSN6_HUMANBioGRID, HPRD, IntAct16169070 details
RFC5_HUMANRFC4_HUMANBioGRID, HPRD, IntAct16189514 22939629 24981860 25416956 26264872 26344197 28514442 29892012 30021884 31515488 32296183 8692848 9092549 9228079 9488738 9751713 details
RFC5_HUMANKRT34_HUMANBioGRID, IntAct32296183 details
RFC5_HUMANEXOS8_HUMANBioGRID, IntAct32296183 details
RFC5_HUMANPCNA_HUMANBioGRID, HPRD12171929 24958773 8999859 9228079 details
RFC5_HUMANRBM48_HUMANBioGRID, HPRD, IntAct16169070 details
RFC5_HUMANGO45_HUMANIntAct32296183 details
RFC5_HUMANLMO3_HUMANBioGRID, IntAct32296183 details
RFC5_HUMANTSNAX_HUMANBioGRID, IntAct32296183 details
RFC5_HUMANARI5A_HUMANBioGRID, IntAct32296183 details
RFC5_HUMANRAD17_HUMANBioGRID, DIP, IntAct14605214 14624239 28514442 details
RFC5_HUMANSUMO2_HUMANBioGRID32786267 details
RFC5_HUMANU119A_HUMANBioGRID, HPRD, IntAct16169070 details
RFC5_HUMANF166B_HUMANBioGRID, IntAct32296183 details
RFC5_HUMANMED31_HUMANBioGRID, HPRD, IntAct16169070 details
RFC5_HUMANBIRC2_HUMANBioGRID, IntAct32296183 details
RFC5_HUMANLRIF1_HUMANBioGRID, HPRD16169070 details
RFC5_HUMANTRI38_HUMANBioGRID, IntAct25416956 29892012 31515488 32296183 details
RFC5_HUMANPP16B_HUMANBioGRID, IntAct32296183 details
RFC5_HUMANZN426_HUMANBioGRID, IntAct32296183 details
RFC5_HUMANNAB2_HUMANBioGRID, IntAct25416956 29892012 31515488 32296183 details
RFC5_HUMANXIAP_HUMANBioGRID, IntAct25416956 29892012 31515488 32296183 details
RFC5_HUMANZNF19_HUMANBioGRID, IntAct32296183 details
RFC5_HUMANSTF1_HUMANBioGRID, IntAct32296183 details
RFC5_HUMANEF1A1_HUMANBioGRID, HPRD, IntAct16169070 details
RFC5_HUMANRFC2_HUMANBioGRID, HPRD, IntAct22939629 24981860 26344197 28514442 8692848 9228079 9488738 9751713 details
RFC5_HUMANCTF18_HUMANBioGRID, IntAct12930902 28514442 details
RFC5_HUMANYPEL3_HUMANBioGRID32296183 details
RFC5_HUMANCCNC_HUMANBioGRID, IntAct32296183 details
RFC5_HUMANBRD4_HUMANBioGRID, MINT12192049 24981860 32416067 details
RFC5_HUMANZMAT1_HUMANBioGRID32296183 details
RFC5_HUMANN4BP3_HUMANBioGRID, IntAct32296183 details
RFC5_HUMANEMAL2_HUMANBioGRID32296183 details
RFC5_HUMANPTEN_HUMANBioGRID31685992 details
RFC5_HUMANTASO2_HUMANBioGRID, IntAct32296183 details
RFC5_HUMANDDT4L_HUMANBioGRID, IntAct32296183 details
RFC5_HUMANDAPK1_HUMANBioGRID, IntAct29513927 details
RFC5_HUMANXAF1_HUMANBioGRID, IntAct32296183 details
RFC5_HUMANEAF6_HUMANIntAct32296183 details
RFC5_HUMANRFC1_HUMANBioGRID, IntAct18245774 22939629 26344197 28514442 9488738 details
RFC5_HUMANRIF1_HUMANIntAct16169070 details
RFC5_HUMANATAD5_HUMANBioGRID, IntAct24981860 28514442 31160570 details
RFC5_HUMANSMRCD_HUMANBioGRID21549307 details
RFC5_HUMANMYSM1_HUMANBioGRID32466590 details
RFC5_HUMANTRI29_HUMANBioGRID26095369 details
RFC5_HUMANMCM9_HUMANBioGRID26300262 26870752 details
RFC5_HUMANRFA1_HUMANBioGRID, MINT24332808 24981860 26474068 details
RFC5_HUMANHUS1_HUMANBioGRID20545769 details
RFC5_HUMANT22D1_HUMANIntAct17353931 details
RFC5_HUMANRAD1_HUMANBioGRID20545769 details
RFC5_HUMANPIDD1_HUMANBioGRID21415862 details
RFC5_HUMANRAD9A_HUMANBioGRID20545769 details