Entity Details

Primary name PI4KA_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP42356
EntryNamePI4KA_HUMAN
FullNamePhosphatidylinositol 4-kinase alpha
TaxID9606
Evidenceevidence at protein level
Length2102
SequenceStatuscomplete
DateCreated1995-11-01
DateModified2021-06-02

Ontological Relatives

GenesPI4KA

GO terms

Show/Hide Table
GOName
GO:0004430 1-phosphatidylinositol 4-kinase activity
GO:0005524 ATP binding
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005925 focal adhesion
GO:0006661 phosphatidylinositol biosynthetic process
GO:0007165 signal transduction
GO:0016020 membrane
GO:0016301 kinase activity
GO:0016310 phosphorylation
GO:0030660 Golgi-associated vesicle membrane
GO:0039694 viral RNA genome replication
GO:0044803 multi-organism membrane organization
GO:0045296 cadherin binding
GO:0046786 viral replication complex formation and maintenance
GO:0046854 phosphatidylinositol phosphate biosynthetic process
GO:0048015 phosphatidylinositol-mediated signaling
GO:0052742 phosphatidylinositol kinase activity
GO:0070062 extracellular exosome

Subcellular Location

Show/Hide Table
Subcellular Location
Cell membrane
Cytoplasm

Domains

Show/Hide Table
DomainNameCategoryType
IPR000403 Phosphatidylinositol 3-/4-kinase, catalytic domainDomainDomain
IPR001263 Phosphoinositide 3-kinase, accessory (PIK) domainDomainDomain
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR015433 Phosphatidylinositol kinaseFamilyFamily
IPR016024 Armadillo-type foldFamilyHomologous superfamily
IPR018936 Phosphatidylinositol 3/4-kinase, conserved siteSiteConserved site
IPR036940 Phosphatidylinositol 3-/4-kinase, catalytic domain superfamilyFamilyHomologous superfamily
IPR042236 Phosphoinositide 3-kinase, accessory (PIK) domain superfamilyFamilyHomologous superfamily

Diseases

Show/Hide Table