Entity Details

Primary name PF2R_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP43088
EntryNamePF2R_HUMAN
FullNameProstaglandin F2-alpha receptor
TaxID9606
Evidenceevidence at protein level
Length359
SequenceStatuscomplete
DateCreated1995-11-01
DateModified2021-06-02

Ontological Relatives

GenesPTGFR

GO terms

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GOName
GO:0004958 prostaglandin F receptor activity
GO:0005576 extracellular region
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006954 inflammatory response
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0007567 parturition
GO:0008284 positive regulation of cell population proliferation
GO:0010628 positive regulation of gene expression
GO:0032355 response to estradiol
GO:0032496 response to lipopolysaccharide
GO:0035584 calcium-mediated signaling using intracellular calcium source
GO:0043066 negative regulation of apoptotic process
GO:0071799 cellular response to prostaglandin D stimulus

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000141 Prostaglandin F receptorFamilyFamily
IPR000276 G protein-coupled receptor, rhodopsin-likeFamilyFamily
IPR008365 Prostanoid receptorFamilyFamily
IPR017452 GPCR, rhodopsin-like, 7TMDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB00287 TravoprostDrugbanksmall molecule
DB00654 LatanoprostDrugbanksmall molecule
DB00905 BimatoprostDrugbanksmall molecule
DB01160 Dinoprost tromethamineDrugbanksmall molecule
DB08819 TafluprostDrugbanksmall molecule
DB11660 Latanoprostene bunodDrugbanksmall molecule