Entity Details

Primary name NEST_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP48681
EntryNameNEST_HUMAN
FullNameNestin
TaxID9606
Evidenceevidence at protein level
Length1621
SequenceStatuscomplete
DateCreated1996-02-01
DateModified2021-06-02

Ontological Relatives

GenesNES

GO terms

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GOName
GO:0000086 G2/M transition of mitotic cell cycle
GO:0005737 cytoplasm
GO:0005882 intermediate filament
GO:0007417 central nervous system development
GO:0007420 brain development
GO:0019215 intermediate filament binding
GO:0030844 positive regulation of intermediate filament depolymerization
GO:0031076 embryonic camera-type eye development
GO:0031730 CCR5 chemokine receptor binding
GO:0032091 negative regulation of protein binding
GO:0043086 negative regulation of catalytic activity
GO:0043524 negative regulation of neuron apoptotic process
GO:0045111 intermediate filament cytoskeleton
GO:0048858 cell projection morphogenesis
GO:0072089 stem cell proliferation
GO:2000179 positive regulation of neural precursor cell proliferation

Subcellular Location

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Domains

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DomainNameCategoryType
IPR018039 Intermediate filament protein, conserved siteSiteConserved site
IPR031211 NestinFamilyFamily
IPR039008 Intermediate filament, rod domainDomainDomain

Diseases

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