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Entity Details
Primary name
T23O_HUMAN
Entity type
UniProt
Source
Source Link
Details
Accession
P48775
EntryName
T23O_HUMAN
FullName
Tryptophan 2,3-dioxygenase
TaxID
9606
Evidence
evidence at protein level
Length
406
SequenceStatus
complete
DateCreated
1996-02-01
DateModified
2021-06-02
Ontological Relatives
Genes
TDO2
GO terms
Show/Hide Table
GO
Name
GO:0004833
tryptophan 2,3-dioxygenase activity
GO:0005829
cytosol
GO:0006569
tryptophan catabolic process
GO:0016597
amino acid binding
GO:0019441
tryptophan catabolic process to kynurenine
GO:0019442
tryptophan catabolic process to acetyl-CoA
GO:0019825
oxygen binding
GO:0020037
heme binding
GO:0042802
identical protein binding
GO:0046872
metal ion binding
GO:0051289
protein homotetramerization
GO:1904842
response to nitroglycerin
Subcellular Location
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Domains
Show/Hide Table
Domain
Name
Category
Type
IPR004981
Tryptophan 2,3-dioxygenase
Family
Family
IPR037217
Tryptophan/Indoleamine 2,3-dioxygenase-like
Family
Homologous superfamily
Diseases
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Drugs
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Drug
Name
Source
Type
DB00150
Tryptophan
Drugbank
small molecule
DB00500
Tolmetin
Drugbank
small molecule
DB00779
Nalidixic acid
Swissprot
small molecule
Interactions
26 interactions
Interactor
Partner
Sources
Publications
Link
T23O_HUMAN
ASML_HUMAN
BioGRID, HPRD, IntAct
16189514
24722188
25416956
28514442
32296183
details
T23O_HUMAN
KDM1A_HUMAN
BioGRID, MINT
23455924
details
T23O_HUMAN
ANM6_HUMAN
BioGRID, MINT
23455924
details
T23O_HUMAN
SDCB1_HUMAN
BioGRID, IntAct
24722188
25416956
32296183
details
T23O_HUMAN
DPM1_HUMAN
BioGRID, IntAct
25416956
25910212
details
T23O_HUMAN
IF4E_HUMAN
BioGRID, IntAct
24722188
25416956
details
T23O_HUMAN
PSA1_HUMAN
BioGRID, IntAct
25416956
details
T23O_HUMAN
MOB3C_HUMAN
BioGRID, IntAct
25416956
details
T23O_HUMAN
ZFY26_HUMAN
BioGRID, IntAct
25416956
32296183
details
T23O_HUMAN
SDCB2_HUMAN
BioGRID, IntAct
25416956
31515488
details
T23O_HUMAN
MOB1A_HUMAN
BioGRID, IntAct
25416956
32296183
details
T23O_HUMAN
NGB_HUMAN
BioGRID, IntAct
25416956
32296183
details
T23O_HUMAN
T23O_HUMAN
BioGRID, IntAct
24722188
25416956
32296183
details
T23O_HUMAN
REL_HUMAN
BioGRID, IntAct
24722188
details
T23O_HUMAN
NMNA1_HUMAN
BioGRID, IntAct
24722188
32296183
details
T23O_HUMAN
P20D2_HUMAN
BioGRID, IntAct
32296183
details
T23O_HUMAN
LNX1_HUMAN
BioGRID, IntAct
32296183
details
T23O_HUMAN
PICK1_HUMAN
BioGRID, IntAct
32296183
details
T23O_HUMAN
NR1D1_HUMAN
BioGRID, IntAct
32296183
details
T23O_HUMAN
CALR_HUMAN
IntAct
32814053
details
T23O_HUMAN
CADH1_HUMAN
IntAct
32814053
details
T23O_HUMAN
ODO2_HUMAN
IntAct
32814053
details
T23O_HUMAN
SAHH2_HUMAN
IntAct
32814053
details
T23O_HUMAN
NEK7_HUMAN
IntAct
32814053
details
T23O_HUMAN
MEOX2_HUMAN
BioGRID
24722188
details
T23O_HUMAN
LMNA_HUMAN
BioGRID
24623722
details
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