Entity Details

Primary name SYAC_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP49588
EntryNameSYAC_HUMAN
FullNameAlanine--tRNA ligase, cytoplasmic
TaxID9606
Evidenceevidence at protein level
Length968
SequenceStatuscomplete
DateCreated1996-02-01
DateModified2021-06-02

Ontological Relatives

GenesAARS1

GO terms

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GOName
GO:0000049 tRNA binding
GO:0002161 aminoacyl-tRNA editing activity
GO:0002196 Ser-tRNA(Ala) hydrolase activity
GO:0004813 alanine-tRNA ligase activity
GO:0005524 ATP binding
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0006400 tRNA modification
GO:0006418 tRNA aminoacylation for protein translation
GO:0006419 alanyl-tRNA aminoacylation
GO:0008033 tRNA processing
GO:0008270 zinc ion binding
GO:0016020 membrane
GO:0016597 amino acid binding
GO:0070062 extracellular exosome

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR002318 Alanine-tRNA ligase, class IIcFamilyFamily
IPR003156 DHHA1 domainDomainDomain
IPR009000 Translation protein, beta-barrel domain superfamilyFamilyHomologous superfamily
IPR012947 Threonyl/alanyl tRNA synthetase, SADDomainDomain
IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamilyFamilyHomologous superfamily
IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamilyFamilyHomologous superfamily
IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminalDomainDomain
IPR018165 Alanyl-tRNA synthetase, class IIc, core domainDomainDomain
IPR023033 Alanine-tRNA ligase, eukaryota/bacteriaFamilyFamily

Diseases

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Drugs

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DrugNameSourceType
DB00160 AlanineDrugbanksmall molecule