Entity Details

Primary name NDUV1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP49821
EntryNameNDUV1_HUMAN
FullNameNADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial
TaxID9606
Evidenceevidence at protein level
Length464
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesNDUFV1

GO terms

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GOName
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005747 mitochondrial respiratory chain complex I
GO:0005829 cytosol
GO:0006120 mitochondrial electron transport, NADH to ubiquinone
GO:0008137 NADH dehydrogenase (ubiquinone) activity
GO:0010181 FMN binding
GO:0032981 mitochondrial respiratory chain complex I assembly
GO:0042775 mitochondrial ATP synthesis coupled electron transport
GO:0046872 metal ion binding
GO:0051287 NAD binding
GO:0051539 4 iron, 4 sulfur cluster binding

Subcellular Location

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Subcellular Location
Mitochondrion inner membrane

Domains

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DomainNameCategoryType
IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved siteSiteConserved site
IPR011537 NADH ubiquinone oxidoreductase, F subunitFamilyFamily
IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domainDomainDomain
IPR019554 Soluble ligand binding domainDomainDomain
IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domainDomainDomain
IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamilyFamilyHomologous superfamily
IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00157 NADHDrugbanksmall molecule