Entity Details

Primary name GDIR2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP52566
EntryNameGDIR2_HUMAN
FullNameRho GDP-dissociation inhibitor 2
TaxID9606
Evidenceevidence at protein level
Length201
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesARHGDIB

GO terms

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GOName
GO:0003924 GTPase activity
GO:0005094 Rho GDP-dissociation inhibitor activity
GO:0005096 GTPase activator activity
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0007162 negative regulation of cell adhesion
GO:0007266 Rho protein signal transduction
GO:0007275 multicellular organism development
GO:0016020 membrane
GO:0031267 small GTPase binding
GO:0031410 cytoplasmic vesicle
GO:0035023 regulation of Rho protein signal transduction
GO:0043547 positive regulation of GTPase activity
GO:0051056 regulation of small GTPase mediated signal transduction
GO:0070062 extracellular exosome
GO:0071461 cellular response to redox state
GO:1901164 negative regulation of trophoblast cell migration
GO:2000249 regulation of actin cytoskeleton reorganization

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR000406 Rho protein GDP-dissociation inhibitorFamilyFamily
IPR014756 Immunoglobulin E-setFamilyHomologous superfamily
IPR024792 Rho GDP-dissociation inhibitor domain superfamilyFamilyHomologous superfamily

Diseases

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