Entity Details

Primary name DGKQ_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP52824
EntryNameDGKQ_HUMAN
FullNameDiacylglycerol kinase theta
TaxID9606
Evidenceevidence at protein level
Length942
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesDGKQ

GO terms

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GOName
GO:0003951 NAD+ kinase activity
GO:0004143 diacylglycerol kinase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005768 endosome
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0005886 plasma membrane
GO:0006111 regulation of gluconeogenesis
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006654 phosphatidic acid biosynthetic process
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007205 protein kinase C-activating G protein-coupled receptor signaling pathway
GO:0008277 regulation of G protein-coupled receptor signaling pathway
GO:0010628 positive regulation of gene expression
GO:0010629 negative regulation of gene expression
GO:0010801 negative regulation of peptidyl-threonine phosphorylation
GO:0012506 vesicle membrane
GO:0016363 nuclear matrix
GO:0016607 nuclear speck
GO:0018105 peptidyl-serine phosphorylation
GO:0019900 kinase binding
GO:0019933 cAMP-mediated signaling
GO:0030168 platelet activation
GO:0030297 transmembrane receptor protein tyrosine kinase activator activity
GO:0033198 response to ATP
GO:0035556 intracellular signal transduction
GO:0043274 phospholipase binding
GO:0046339 diacylglycerol metabolic process
GO:0046486 glycerolipid metabolic process
GO:0046834 lipid phosphorylation
GO:0046872 metal ion binding
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
GO:0051591 response to cAMP
GO:0070493 thrombin-activated receptor signaling pathway
GO:0070528 protein kinase C signaling
GO:0090181 regulation of cholesterol metabolic process
GO:0098793 presynapse
GO:0098794 postsynapse
GO:0098978 glutamatergic synapse
GO:1900242 regulation of synaptic vesicle endocytosis
GO:1903432 regulation of TORC1 signaling
GO:2000064 regulation of cortisol biosynthetic process
GO:2000182 regulation of progesterone biosynthetic process

Subcellular Location

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Subcellular Location
Cell junction
Cell membrane
Cytoplasm
Nucleus
Nucleus matrix
Nucleus speckle

Domains

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DomainNameCategoryType
IPR000159 Ras-associating (RA) domainDomainDomain
IPR000756 Diacylglycerol kinase, accessory domainDomainDomain
IPR001206 Diacylglycerol kinase, catalytic domainDomainDomain
IPR002219 Protein kinase C-like, phorbol ester/diacylglycerol-binding domainDomainDomain
IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamilyFamilyHomologous superfamily
IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminalFamilyHomologous superfamily
IPR029071 Ubiquitin-like domain superfamilyFamilyHomologous superfamily
IPR037607 Diacylglycerol kinaseFamilyFamily

Diseases

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Drugs

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DrugNameSourceType
DB14001 alpha-Tocopherol succinateDrugbanksmall molecule

Interactions

4 interactions