Entity Details

Primary name EPHB3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP54753
EntryNameEPHB3_HUMAN
FullNameEphrin type-B receptor 3
TaxID9606
Evidenceevidence at protein level
Length998
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesEPHB3

GO terms

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GOName
GO:0001525 angiogenesis
GO:0001655 urogenital system development
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0005003 ephrin receptor activity
GO:0005005 transmembrane-ephrin receptor activity
GO:0005524 ATP binding
GO:0005576 extracellular region
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007275 multicellular organism development
GO:0007411 axon guidance
GO:0007413 axonal fasciculation
GO:0008046 axon guidance receptor activity
GO:0016477 cell migration
GO:0021952 central nervous system projection neuron axonogenesis
GO:0022038 corpus callosum development
GO:0022407 regulation of cell-cell adhesion
GO:0030425 dendrite
GO:0031290 retinal ganglion cell axon guidance
GO:0033674 positive regulation of kinase activity
GO:0034446 substrate adhesion-dependent cell spreading
GO:0043005 neuron projection
GO:0043087 regulation of GTPase activity
GO:0043235 receptor complex
GO:0046777 protein autophosphorylation
GO:0048013 ephrin receptor signaling pathway
GO:0048538 thymus development
GO:0048546 digestive tract morphogenesis
GO:0050770 regulation of axonogenesis
GO:0051965 positive regulation of synapse assembly
GO:0060021 roof of mouth development
GO:0060996 dendritic spine development
GO:0060997 dendritic spine morphogenesis

Subcellular Location

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Subcellular Location
Cell membrane
Cell projection

Domains

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DomainNameCategoryType
IPR000719 Protein kinase domainDomainDomain
IPR001090 Ephrin receptor ligand binding domainDomainDomain
IPR001245 Serine-threonine/tyrosine-protein kinase, catalytic domainDomainDomain
IPR001426 Tyrosine-protein kinase, receptor class V, conserved siteSiteConserved site
IPR001660 Sterile alpha motif domainDomainDomain
IPR003961 Fibronectin type IIIDomainDomain
IPR008266 Tyrosine-protein kinase, active siteSiteActive site
IPR008979 Galactose-binding-like domain superfamilyFamilyHomologous superfamily
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR011641 Tyrosine-protein kinase ephrin type A/B receptor-likeDomainDomain
IPR013761 Sterile alpha motif/pointed domain superfamilyFamilyHomologous superfamily
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR016257 Ephrin receptor type-A /type-BFamilyFamily
IPR017441 Protein kinase, ATP binding siteSiteBinding site
IPR020635 Tyrosine-protein kinase, catalytic domainDomainDomain
IPR027936 Ephrin receptor, transmembrane domainDomainDomain
IPR034245 Ephrin type-B receptor 3, ligand binding domainDomainDomain
IPR036116 Fibronectin type III superfamilyFamilyHomologous superfamily

Diseases

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