Entity Details

Primary name RAB8A_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP61006
EntryNameRAB8A_HUMAN
FullNameRas-related protein Rab-8A
TaxID9606
Evidenceevidence at protein level
Length207
SequenceStatuscomplete
DateCreated2004-04-26
DateModified2021-06-02

Ontological Relatives

GenesRAB8A

GO terms

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GOName
GO:0000139 Golgi membrane
GO:0003924 GTPase activity
GO:0005525 GTP binding
GO:0005768 endosome
GO:0005813 centrosome
GO:0005814 centriole
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005929 cilium
GO:0006904 vesicle docking involved in exocytosis
GO:0006914 autophagy
GO:0007409 axonogenesis
GO:0008021 synaptic vesicle
GO:0009306 protein secretion
GO:0010506 regulation of autophagy
GO:0014069 postsynaptic density
GO:0017157 regulation of exocytosis
GO:0019003 GDP binding
GO:0019901 protein kinase binding
GO:0030140 trans-Golgi network transport vesicle
GO:0030496 midbody
GO:0030670 phagocytic vesicle membrane
GO:0031267 small GTPase binding
GO:0031489 myosin V binding
GO:0032588 trans-Golgi network membrane
GO:0032869 cellular response to insulin stimulus
GO:0043025 neuronal cell body
GO:0043197 dendritic spine
GO:0043687 post-translational protein modification
GO:0045335 phagocytic vesicle
GO:0048169 regulation of long-term neuronal synaptic plasticity
GO:0048210 Golgi vesicle fusion to target membrane
GO:0051223 regulation of protein transport
GO:0055038 recycling endosome membrane
GO:0060271 cilium assembly
GO:0070062 extracellular exosome
GO:0072659 protein localization to plasma membrane
GO:0097730 non-motile cilium
GO:0098887 neurotransmitter receptor transport, endosome to postsynaptic membrane
GO:0098969 neurotransmitter receptor transport to postsynaptic membrane
GO:0098978 glutamatergic synapse
GO:0099003 vesicle-mediated transport in synapse

Subcellular Location

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Subcellular Location
Cell membrane
Cell projection
Cytoplasm
Cytoplasmic vesicle
Golgi apparatus
Midbody
Recycling endosome membrane

Domains

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DomainNameCategoryType
IPR001806 Small GTPaseFamilyFamily
IPR005225 Small GTP-binding protein domainDomainDomain
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily

Diseases

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Interactions

72 interactions

InteractorPartnerSourcesPublicationsLink
RAB8A_HUMANTFR1_HUMANBioGRID, UniProt20085643 22854040 details
RAB8A_HUMANOCRL_HUMANBioGRID, HPRD, IntAct, MINT, UniProt16902405 21378754 26824392 29125462 details
RAB8A_HUMANSYTL4_HUMANBioGRID, HPRD, IntAct, UniProt11773082 12176990 12590134 23140275 24700782 26553929 26824392 29125462 details
RAB8A_HUMANR3GEF_HUMANBioGRID, IntAct26186194 26918858 28514442 details
RAB8A_HUMANBAG6_HUMANBioGRID, HPRD, IntAct16169070 30804014 details
RAB8A_HUMANMYO5B_HUMANBioGRID17507647 26553929 details
RAB8A_HUMANOPTN_HUMANBioGRID, HPRD, UniProt11137014 20085643 20161783 20388642 20634958 22854040 23357852 details
RAB8A_HUMANDCDC1_HUMANBioGRID22159412 details
RAB8A_HUMANRAB3I_HUMANBioGRID, DIP, HPRD, IntAct12221131 123217 20308558 21273506 26258637 26824392 26918858 27173435 unassigned1312 details
RAB8A_HUMANLRRK2_HUMANIntAct26824392 32017888 details
RAB8A_HUMANGDIB_HUMANBioGRID, DIP, HPRD, IntAct, UniProt10512627 25860027 26344197 26824392 29125462 details
RAB8A_HUMANSYTL1_HUMANBioGRID23140275 details
RAB8A_HUMANNEMO_HUMANBioGRID26258637 details
RAB8A_HUMANMDM2_HUMANBioGRID24583282 details
RAB8A_HUMANRB11A_HUMANBioGRID26258637 details
RAB8A_HUMANRAB13_HUMANBioGRID21795389 details
RAB8A_HUMANMSS4_HUMANHPRD, IntAct, MINT, UniProt16541104 26824392 29125462 details
RAB8A_HUMANMYO5C_HUMANBioGRID17507647 details
RAB8A_HUMANSTK24_HUMANIntAct32017888 details
RAB8A_HUMANODFP2_HUMANBioGRID17646400 details
RAB8A_HUMANM4K2_HUMANBioGRID, HPRD8643544 details
RAB8A_HUMANPDE6D_HUMANHPRD16473576 details
RAB8A_HUMANPQBP1_HUMANHPRD, IntAct16169070 details
RAB8A_HUMANSTOM_HUMANBioGRID, IntAct27173435 unassigned1312 details
RAB8A_HUMANRP3A_HUMANBioGRID, HPRD, IntAct12578829 28514442 details
RAB8A_HUMANCYBP_HUMANBioGRID31213539 details
RAB8A_HUMANBIRC6_HUMANBioGRID, HPRD18329369 31213539 details
RAB8A_HUMANBBS1_HUMANBioGRID, IntAct27173435 unassigned1312 details
RAB8A_HUMANMAEA_HUMANBioGRID, IntAct27173435 unassigned1312 details
RAB8A_HUMANYPEL5_HUMANBioGRID, IntAct27173435 unassigned1312 details
RAB8A_HUMANRNF41_HUMANBioGRID31213539 details
RAB8A_HUMANSYUA_HUMANBioGRID, IntAct15207266 24983211 details
RAB8A_HUMANRANB9_HUMANBioGRID, IntAct27173435 unassigned1312 details
RAB8A_HUMANWDR26_HUMANBioGRID, IntAct27173435 unassigned1312 details
RAB8A_HUMANRIPL2_HUMANIntAct, UniProt29125462 32017888 details
RAB8A_HUMANTRI25_HUMANMINT24515439 details
RAB8A_HUMANEXOC6_HUMANBioGRID, IntAct26553929 27173435 unassigned1312 details
RAB8A_HUMANNDUA5_HUMANBioGRID, IntAct27173435 unassigned1312 details
RAB8A_HUMANEHD3_HUMANBioGRID17507647 details
RAB8A_HUMANLAX1_HUMANMINT24515439 details
RAB8A_HUMANSAM50_HUMANBioGRID, IntAct27173435 unassigned1312 details
RAB8A_HUMANARMC8_HUMANBioGRID, IntAct27173435 unassigned1312 details
RAB8A_HUMANJIP4_HUMANIntAct, UniProt29125462 32017888 details
RAB8A_HUMANSQSTM_HUMANMINT27103069 details
RAB8A_HUMANBIN1_HUMANBioGRID26833786 details
RAB8A_HUMANARF6_HUMANUniProt21951725 details
RAB8A_HUMANTBC17_HUMANBioGRID, UniProt22854040 details
RAB8A_HUMANCTLA4_HUMANMINT24515439 details
RAB8A_HUMANJIP3_HUMANIntAct32017888 details
RAB8A_HUMANCE290_HUMANUniProt18694559 details
RAB8A_HUMANMKLN1_HUMANBioGRID, IntAct27173435 unassigned1312 details
RAB8A_HUMANRIMS2_HUMANHPRD12578829 details
RAB8A_HUMANGID8_HUMANBioGRID, IntAct27173435 unassigned1312 details
RAB8A_HUMANFLCN_HUMANBioGRID28656962 details
RAB8A_HUMANEPB41_HUMANIntAct17353931 details
RAB8A_HUMANEH1L1_HUMANBioGRID, UniProt26833786 29125462 details
RAB8A_HUMANRAB3B_HUMANBioGRID26553929 details
RAB8A_HUMANMTMR4_HUMANBioGRID27432908 details
RAB8A_HUMANMIC19_HUMANBioGRID, IntAct27173435 unassigned1312 details
RAB8A_HUMANEHD1_HUMANBioGRID, UniProt17507647 19864458 details
RAB8A_HUMANVAMP3_HUMANBioGRID26553929 details
RAB8A_HUMANEXOC5_HUMANBioGRID, IntAct27173435 unassigned1312 details
RAB8A_HUMANNDUAA_HUMANBioGRID, IntAct27173435 unassigned1312 details
RAB8A_HUMANRMD5A_HUMANBioGRID, IntAct27173435 unassigned1312 details
RAB8A_HUMANRBP10_HUMANBioGRID, IntAct27173435 unassigned1312 details
RAB8A_HUMANRMD5B_HUMANBioGRID, IntAct27173435 unassigned1312 details
RAB8A_HUMANSMCR8_HUMANMINT27103069 details
RAB8A_HUMANEXOC8_HUMANBioGRID, IntAct27173435 unassigned1312 details
RAB8A_HUMANSTX3_HUMANBioGRID26553929 details
RAB8A_HUMANRPH3L_HUMANHPRD12578829 details
RAB8A_HUMANRIPL1_HUMANUniProt29125462 details
RAB8A_HUMANMLP3B_HUMANBioGRID31213539 details