Entity Details

Primary name STX1B_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP61266
EntryNameSTX1B_HUMAN
FullNameSyntaxin-1B
TaxID9606
Evidenceevidence at protein level
Length288
SequenceStatuscomplete
DateCreated2004-05-10
DateModified2021-06-02

Ontological Relatives

GenesSTX1B

GO terms

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GOName
GO:0000149 SNARE binding
GO:0001956 positive regulation of neurotransmitter secretion
GO:0005102 signaling receptor binding
GO:0005484 SNAP receptor activity
GO:0005634 nucleus
GO:0005652 nuclear lamina
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005815 microtubule organizing center
GO:0005819 spindle
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006886 intracellular protein transport
GO:0006887 exocytosis
GO:0006904 vesicle docking involved in exocytosis
GO:0006906 vesicle fusion
GO:0008021 synaptic vesicle
GO:0010468 regulation of gene expression
GO:0010807 regulation of synaptic vesicle priming
GO:0010977 negative regulation of neuron projection development
GO:0012505 endomembrane system
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016081 synaptic vesicle docking
GO:0017157 regulation of exocytosis
GO:0019901 protein kinase binding
GO:0019904 protein domain specific binding
GO:0030424 axon
GO:0031201 SNARE complex
GO:0031594 neuromuscular junction
GO:0031629 synaptic vesicle fusion to presynaptic active zone membrane
GO:0048278 vesicle docking
GO:0048787 presynaptic active zone membrane
GO:0048791 calcium ion-regulated exocytosis of neurotransmitter
GO:0060025 regulation of synaptic activity
GO:0061669 spontaneous neurotransmitter secretion
GO:0098967 exocytic insertion of neurotransmitter receptor to postsynaptic membrane
GO:1903422 negative regulation of synaptic vesicle recycling
GO:1904050 positive regulation of spontaneous neurotransmitter secretion
GO:1905302 negative regulation of macropinocytosis
GO:2000463 positive regulation of excitatory postsynaptic potential

Subcellular Location

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Subcellular Location
Cytoplasm
Membrane
Nucleus

Domains

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DomainNameCategoryType
IPR000727 Target SNARE coiled-coil homology domainDomainDomain
IPR006011 Syntaxin, N-terminal domainDomainDomain
IPR006012 Syntaxin/epimorphin, conserved siteSiteConserved site
IPR010989 SNAREFamilyHomologous superfamily
IPR028669 Syntaxin 1FamilyFamily

Diseases

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Interactions

32 interactions

InteractorPartnerSourcesPublicationsLink
STX1B_HUMANSNP23_HUMANBioGRID, IntAct12651853 26359495 details
STX1B_HUMANSNP47_HUMANBioGRID, IntAct32296183 details
STX1B_HUMANSNAB_HUMANBioGRID, IntAct32296183 details
STX1B_HUMANTXLNA_HUMANBioGRID, IntAct32296183 details
STX1B_HUMANVAMP5_HUMANBioGRID, IntAct32296183 details
STX1B_HUMANBET1_HUMANBioGRID, IntAct32296183 details
STX1B_HUMANSTX2_HUMANBioGRID, IntAct32296183 details
STX1B_HUMANVAMP1_HUMANBioGRID, HPRD, IntAct12093152 32296183 details
STX1B_HUMANF161B_HUMANBioGRID, IntAct32296183 details
STX1B_HUMANACBD5_HUMANBioGRID, IntAct32296183 details
STX1B_HUMANFA81A_HUMANBioGRID, IntAct32296183 details
STX1B_HUMANAQP6_HUMANBioGRID, IntAct32296183 details
STX1B_HUMANKCNN4_HUMANBioGRID, IntAct32296183 details
STX1B_HUMANERGI3_HUMANBioGRID, IntAct32296183 details
STX1B_HUMANEMC5_HUMANBioGRID, IntAct32296183 details
STX1B_HUMANGP152_HUMANBioGRID, IntAct32296183 details
STX1B_HUMANEBP_HUMANBioGRID, IntAct32296183 details
STX1B_HUMANSTX4_HUMANBioGRID, IntAct32296183 details
STX1B_HUMANSNP29_HUMANBioGRID, IntAct32296183 details
STX1B_HUMANVAMP2_HUMANBioGRID, HPRD, IntAct12093152 32296183 details
STX1B_HUMANFBX28_HUMANBioGRID, IntAct32296183 details
STX1B_HUMANABHGA_HUMANBioGRID, IntAct32296183 details
STX1B_HUMANCXA8_HUMANBioGRID, IntAct32296183 details
STX1B_HUMANKISHB_HUMANBioGRID, IntAct32296183 details
STX1B_HUMANFIBA_HUMANBioGRID, IntAct32296183 details
STX1B_HUMANF209A_HUMANBioGRID, IntAct32296183 details
STX1B_HUMANSTXB1_HUMANBioGRID, HPRD, IntAct12093152 31413325 details
STX1B_HUMANUN13B_HUMANBioGRID, HPRD8999968 details
STX1B_HUMANVAPB_HUMANBioGRID12651853 24885147 details
STX1B_HUMANUBC9_HUMANBioGRID32296183 details
STX1B_HUMANDISC1_HUMANIntAct31413325 details
STX1B_HUMANVAMP8_HUMANHPRD11112705 details