Entity Details

Primary name IL5RA_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ01344
EntryNameIL5RA_HUMAN
FullNameInterleukin-5 receptor subunit alpha
TaxID9606
Evidenceevidence at protein level
Length420
SequenceStatuscomplete
DateCreated1993-07-01
DateModified2021-06-02

Ontological Relatives

GenesIL5RA

GO terms

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GOName
GO:0000165 MAPK cascade
GO:0002437 inflammatory response to antigenic stimulus
GO:0004896 cytokine receptor activity
GO:0004914 interleukin-5 receptor activity
GO:0005615 extracellular space
GO:0005886 plasma membrane
GO:0007165 signal transduction
GO:0009897 external side of plasma membrane
GO:0016021 integral component of membrane
GO:0019221 cytokine-mediated signaling pathway
GO:0019955 cytokine binding
GO:0032674 regulation of interleukin-5 production
GO:0043235 receptor complex
GO:0070665 positive regulation of leukocyte proliferation

Subcellular Location

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Subcellular Location
Membrane

Domains

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DomainNameCategoryType
IPR003532 Short hematopoietin receptor, family 2, conserved siteSiteConserved site
IPR003961 Fibronectin type IIIDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR015321 Type I cytokine receptor, cytokine-binding domainDomainDomain
IPR036116 Fibronectin type III superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB12023 BenralizumabDrugbankbiotech