Entity Details

Primary name KIME_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ03426
EntryNameKIME_HUMAN
FullNameMevalonate kinase
TaxID9606
Evidenceevidence at protein level
Length396
SequenceStatuscomplete
DateCreated1993-10-01
DateModified2021-06-02

Ontological Relatives

GenesMVK

GO terms

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GOName
GO:0000287 magnesium ion binding
GO:0004496 mevalonate kinase activity
GO:0005524 ATP binding
GO:0005777 peroxisome
GO:0005829 cytosol
GO:0006695 cholesterol biosynthetic process
GO:0008299 isoprenoid biosynthetic process
GO:0019216 regulation of lipid metabolic process
GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway
GO:0042802 identical protein binding
GO:0043231 intracellular membrane-bounded organelle
GO:0050728 negative regulation of inflammatory response

Subcellular Location

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Subcellular Location
Cytoplasm
Peroxisome

Domains

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DomainNameCategoryType
IPR006203 GHMP kinase, ATP-binding, conserved siteSiteConserved site
IPR006204 GHMP kinase N-terminal domainDomainDomain
IPR006205 Mevalonate kinaseFamilyFamily
IPR013750 GHMP kinase, C-terminal domainDomainDomain
IPR014721 Ribosomal protein S5 domain 2-type fold, subgroupFamilyHomologous superfamily
IPR020568 Ribosomal protein S5 domain 2-type foldFamilyHomologous superfamily
IPR036554 GHMP kinase, C-terminal domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB04695 Farnesyl thiopyrophosphateDrugbanksmall molecule

Interactions

5 interactions