Entity Details

Primary name RN5A_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ05823
EntryNameRN5A_HUMAN
FullName2-5A-dependent ribonuclease
TaxID9606
Evidenceevidence at protein level
Length741
SequenceStatuscomplete
DateCreated1995-11-01
DateModified2021-06-02

Ontological Relatives

GenesRNASEL

GO terms

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GOName
GO:0003723 RNA binding
GO:0004521 endoribonuclease activity
GO:0004540 ribonuclease activity
GO:0004672 protein kinase activity
GO:0005524 ATP binding
GO:0005759 mitochondrial matrix
GO:0005829 cytosol
GO:0006364 rRNA processing
GO:0006396 RNA processing
GO:0006397 mRNA processing
GO:0006468 protein phosphorylation
GO:0016363 nuclear matrix
GO:0019843 rRNA binding
GO:0042802 identical protein binding
GO:0043021 ribonucleoprotein complex binding
GO:0043488 regulation of mRNA stability
GO:0045071 negative regulation of viral genome replication
GO:0045444 fat cell differentiation
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046326 positive regulation of glucose import
GO:0046872 metal ion binding
GO:0051607 defense response to virus
GO:0060337 type I interferon signaling pathway
GO:0060338 regulation of type I interferon-mediated signaling pathway

Subcellular Location

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Subcellular Location
Cytoplasm
Mitochondrion

Domains

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DomainNameCategoryType
IPR000719 Protein kinase domainDomainDomain
IPR002110 Ankyrin repeatRepeatRepeat
IPR010513 KEN domainDomainDomain
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR020683 Ankyrin repeat-containing domainDomainDomain
IPR036770 Ankyrin repeat-containing domain superfamilyFamilyHomologous superfamily
IPR038357 KEN domain superfamilyFamilyHomologous superfamily
IPR042745 RNase L, RNase domainDomainDomain

Diseases

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