Entity Details

Primary name SH2B3
Entity type gene
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Details

PrimaryID10019
RefseqGeneNG_021216
SymbolSH2B3
NameSH2B adaptor protein 3
Chromosome12
Location12q24.12
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-05-13
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsSH2B3_HUMAN

GO terms

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GOName
GO:0001780 neutrophil homeostasis
GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity
GO:0005173 stem cell factor receptor binding
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0007596 blood coagulation
GO:0008285 negative regulation of cell population proliferation
GO:0019221 cytokine-mediated signaling pathway
GO:0030159 signaling receptor complex adaptor activity
GO:0035162 embryonic hemopoiesis
GO:0035556 intracellular signal transduction
GO:0035702 monocyte homeostasis
GO:0035855 megakaryocyte development
GO:0036016 cellular response to interleukin-3
GO:0038163 thrombopoietin-mediated signaling pathway
GO:0042532 negative regulation of tyrosine phosphorylation of STAT protein
GO:0043407 negative regulation of MAP kinase activity
GO:0046426 negative regulation of receptor signaling pathway via JAK-STAT
GO:0048821 erythrocyte development
GO:0051898 negative regulation of protein kinase B signaling
GO:0060761 negative regulation of response to cytokine stimulus
GO:0070100 negative regulation of chemokine-mediated signaling pathway
GO:0090331 negative regulation of platelet aggregation
GO:1900235 negative regulation of Kit signaling pathway
GO:1990782 protein tyrosine kinase binding
GO:1990869 cellular response to chemokine

Diseases

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