Entity Details

Primary name PLA2R_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ13018
EntryNamePLA2R_HUMAN
FullNameSecretory phospholipase A2 receptor
TaxID9606
Evidenceevidence at protein level
Length1463
SequenceStatuscomplete
DateCreated2007-11-13
DateModified2021-06-02

Ontological Relatives

GenesPLA2R1

GO terms

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GOName
GO:0001819 positive regulation of cytokine production
GO:0005576 extracellular region
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006898 receptor-mediated endocytosis
GO:0009986 cell surface
GO:0016021 integral component of membrane
GO:0030246 carbohydrate binding
GO:0038023 signaling receptor activity
GO:0043235 receptor complex
GO:0043274 phospholipase binding
GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator
GO:0072593 reactive oxygen species metabolic process
GO:0090238 positive regulation of arachidonic acid secretion
GO:0090399 replicative senescence
GO:0090403 oxidative stress-induced premature senescence
GO:1900138 negative regulation of phospholipase A2 activity
GO:1900139 negative regulation of arachidonic acid secretion
GO:1904635 positive regulation of glomerular visceral epithelial cell apoptotic process

Subcellular Location

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Subcellular Location
Cell membrane
Secreted

Domains

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DomainNameCategoryType
IPR000562 Fibronectin type II domainDomainDomain
IPR000772 Ricin B, lectin domainDomainDomain
IPR001304 C-type lectin-likeDomainDomain
IPR016186 C-type lectin-like/link domain superfamilyFamilyHomologous superfamily
IPR016187 C-type lectin foldFamilyHomologous superfamily
IPR018378 C-type lectin, conserved siteSiteConserved site
IPR035992 Ricin B-like lectinsFamilyHomologous superfamily
IPR036943 Fibronectin type II domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
PLA2R_HUMANPA2GA_HUMANHPRD7721806 details
PLA2R_HUMANPA2GX_HUMANHPRD10922494 11019817 details