Entity Details

Primary name STF1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ13285
EntryNameSTF1_HUMAN
FullNameSteroidogenic factor 1
TaxID9606
Evidenceevidence at protein level
Length461
SequenceStatuscomplete
DateCreated1998-07-15
DateModified2021-06-02

Ontological Relatives

GenesNR5A1

GO terms

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GOName
GO:0000785 chromatin
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001553 luteinization
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0004879 nuclear receptor activity
GO:0005543 phospholipid binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005829 cytosol
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006367 transcription initiation from RNA polymerase II promoter
GO:0007530 sex determination
GO:0007538 primary sex determination
GO:0008270 zinc ion binding
GO:0008584 male gonad development
GO:0008585 female gonad development
GO:0009755 hormone-mediated signaling pathway
GO:0009888 tissue development
GO:0010259 multicellular organism aging
GO:0010628 positive regulation of gene expression
GO:0019899 enzyme binding
GO:0030154 cell differentiation
GO:0030238 male sex determination
GO:0030325 adrenal gland development
GO:0042445 hormone metabolic process
GO:0043565 sequence-specific DNA binding
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0050810 regulation of steroid biosynthetic process
GO:0051457 maintenance of protein location in nucleus
GO:0090575 RNA polymerase II transcription regulator complex
GO:0097210 response to gonadotropin-releasing hormone
GO:0097720 calcineurin-mediated signaling
GO:1990837 sequence-specific double-stranded DNA binding
GO:2000020 positive regulation of male gonad development
GO:2000195 negative regulation of female gonad development

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR000536 Nuclear hormone receptor, ligand-binding domainDomainDomain
IPR001628 Zinc finger, nuclear hormone receptor-typeDomainDomain
IPR001723 Nuclear hormone receptorFamilyFamily
IPR013088 Zinc finger, NHR/GATA-typeFamilyHomologous superfamily
IPR016355 Nuclear hormone receptor family 5FamilyFamily
IPR035500 Nuclear hormone receptor-like domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB04683 (2R)-3-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-[(9E)-HEXADEC-9-ENOYLOXY]PROPYL (9E)-OCTADEC-9-ENOATEDrugbanksmall molecule
DB04752 Phosphatidyl ethanolDrugbanksmall molecule

Interactions

43 interactions

InteractorPartnerSourcesPublicationsLink
STF1_HUMANPNRC2_HUMANHPRD, MINT11574675 details
STF1_HUMANCRK_HUMANIntAct17474147 details
STF1_HUMANFYN_HUMANIntAct17474147 details
STF1_HUMANGRB2_HUMANIntAct17474147 details
STF1_HUMANNCK1_HUMANIntAct17474147 details
STF1_HUMANP85A_HUMANIntAct17474147 details
STF1_HUMANPROX1_HUMANbhf-ucl, HPRD16488887 details
STF1_HUMANJUN_HUMANBioGRID, HPRD, IntAct10478848 24635384 details
STF1_HUMANNCK2_HUMANBioGRID, IntAct25416956 details
STF1_HUMANNR0B1_HUMANBioGRID, HPRD, IntAct11459805 11713202 14963109 25416956 25910212 32296183 details
STF1_HUMANDUX4C_HUMANIntAct26816005 details
STF1_HUMANRFC5_HUMANBioGRID, IntAct32296183 details
STF1_HUMANNTAQ1_HUMANBioGRID, IntAct32296183 details
STF1_HUMANC2CD6_HUMANBioGRID, IntAct32296183 details
STF1_HUMANTEKT4_HUMANBioGRID, IntAct32296183 details
STF1_HUMANCKS1_HUMANBioGRID, IntAct32296183 details
STF1_HUMANCXXC1_HUMANBioGRID, IntAct20211142 details
STF1_HUMANSOX9_HUMANBioGRID, HPRD9774680 details
STF1_HUMANNRIP1_HUMANBioGRID, HPRD11459805 12782406 details
STF1_HUMANZN653_HUMANBioGRID, HPRD12920234 details
STF1_HUMANGATA4_HUMANBioGRID, HPRD10446911 details
STF1_HUMANNCOA1_HUMANBioGRID, HPRD9328345 details
STF1_HUMANTREF1_HUMANBioGRID, HPRD12101186 details
STF1_HUMANCTNB1_HUMANBioGRID, HPRD12554773 details
STF1_HUMANPITX1_HUMANBioGRID, HPRD10369682 details
STF1_HUMANTF2B_HUMANBioGRID, HPRD10478848 details
STF1_HUMANSP1_HUMANBioGRID, HPRD10919277 details
STF1_HUMANCBP_HUMANBioGRID10628748 details
STF1_HUMANARIP4_HUMANBioGRID19692572 details
STF1_HUMANUBC9_HUMANBioGRID19692572 details
STF1_HUMANTPC2A_HUMANBioGRID20498720 details
STF1_HUMANTPC2B_HUMANBioGRID20498720 details
STF1_HUMANPIAS1_HUMANHPRD15192080 details
STF1_HUMANEDF1_HUMANBioGRID, HPRD, IntAct10567391 details
STF1_HUMANBARD1_HUMANBioGRID21087664 details
STF1_HUMANMK01_HUMANHPRD10230405 details
STF1_HUMANNFYA_HUMANHPRD12730328 details
STF1_HUMANTBX19_HUMANHPRD12651892 details
STF1_HUMANSOX2_HUMANHPRD12732652 details
STF1_HUMANSOX8_HUMANHPRD12732652 details
STF1_HUMANANDR_HUMANHPRD11518799 details
STF1_HUMANNFKB2_HUMANHPRD12917325 details
STF1_HUMANSMRD3_HUMANHPRD14701856 details